TY - JOUR
T1 - Clinical implications for exercise at altitude among individuals with cardiovascular disease
T2 - A scientific statement from the american heart association
AU - Cornwell, William K.
AU - Baggish, Aaron L.
AU - Bhatta, Yadav Kumar Deo
AU - Brosnan, Maria Joan
AU - Dehnert, Christoph
AU - Sawalla Guseh, J.
AU - Hammer, Debra
AU - Levine, Benjamin D.
AU - Parati, Gianfranco
AU - Wolfel, Eugene E.
N1 - Publisher Copyright:
© 2021 The Authors.
PY - 2021/10/5
Y1 - 2021/10/5
N2 - An increasing number of individuals travel to mountainous environments for work and pleasure. However, oxy¬gen availability declines at altitude, and hypoxic environments place unique stressors on the cardiovascular system. These stressors may be exacerbated by exercise at altitude, because exercise increases oxygen demand in an environment that is already relatively oxygen deplete compared with sea-1 evel conditions. Furthermore, the prevalence of cardiovascular disease, as well as diseases such as hypertension, heart failure, and lung disease, is high among individuals living in the United States. As such, patients who are at risk of or who have established cardiovascular disease may be at an increased risk of adverse events when sojourning to these mountainous locations. However, these risks may be minimized by appropriate pretravel assessments and planning through shared decision-making between patients and their managing clinicians. This American Heart Association scientific statement provides a concise, yet comprehensive overview of the physiologic responses to exer¬cise in hypoxic locations, as well as important considerations for minimizing the risk of adverse cardiovascular events during mountainous excursions.
AB - An increasing number of individuals travel to mountainous environments for work and pleasure. However, oxy¬gen availability declines at altitude, and hypoxic environments place unique stressors on the cardiovascular system. These stressors may be exacerbated by exercise at altitude, because exercise increases oxygen demand in an environment that is already relatively oxygen deplete compared with sea-1 evel conditions. Furthermore, the prevalence of cardiovascular disease, as well as diseases such as hypertension, heart failure, and lung disease, is high among individuals living in the United States. As such, patients who are at risk of or who have established cardiovascular disease may be at an increased risk of adverse events when sojourning to these mountainous locations. However, these risks may be minimized by appropriate pretravel assessments and planning through shared decision-making between patients and their managing clinicians. This American Heart Association scientific statement provides a concise, yet comprehensive overview of the physiologic responses to exer¬cise in hypoxic locations, as well as important considerations for minimizing the risk of adverse cardiovascular events during mountainous excursions.
KW - AHA Scientific Statements
KW - Altitude
KW - Cardiovascular diseases
KW - Exercise
KW - Heart failure
KW - Hypertension
UR - http://www.scopus.com/inward/record.url?scp=85118097320&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85118097320&partnerID=8YFLogxK
U2 - 10.1161/JAHA.121.023225
DO - 10.1161/JAHA.121.023225
M3 - Article
C2 - 34496612
AN - SCOPUS:85118097320
SN - 2047-9980
VL - 10
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 19
M1 - e023225
ER -