Clinical magnetic resonance spectroscopy: A critical evaluation

R. E. Lenkinski

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The present status of magnetic resonance spectroscopy (MRS) in the clinical radiology setting is discussed critically. The number of groups reporting clinical MRS results has increased, indicating the feasibility of performing localized MRS studies on current 1.5 T whole body MR imagers. However the lack of high quality radiofrequency (RF) coils for MRS and proven user-independent methods for the analysis of spectral data is still hampering further development. At present there is no consensus as to the optimal localization scheme which should be employed for phosphorus (31P) MRS. For proton MRS the stimulated echo sequence is gaining wide acceptance. The minimum voxel sizes achievable for proton and 31P MRS in the brain are calculated to be 2 and 30 cm3, respectively. The recent results obtained with proton decoupling for 31P clearly demonstrate that there is a great deal of improvement possible in the quality of localized 31P spectra at 1.5 T. Both the instrument manufacturers and researchers in the field face important challenges in translating methods which have proven feasibility in the research environment into routine clinical protocols.

Original languageEnglish (US)
Pages (from-to)1034-1038
Number of pages5
JournalInvestigative Radiology
Volume24
Issue number12
StatePublished - 1989

Fingerprint

Magnetic Resonance Spectroscopy
Clinical Protocols
Radiology
Phosphorus
Protons
Research Personnel
Brain
Research
Proton Magnetic Resonance Spectroscopy

Keywords

  • clinical
  • magnetic
  • resonance
  • spectroscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Clinical magnetic resonance spectroscopy : A critical evaluation. / Lenkinski, R. E.

In: Investigative Radiology, Vol. 24, No. 12, 1989, p. 1034-1038.

Research output: Contribution to journalArticle

Lenkinski, R. E. / Clinical magnetic resonance spectroscopy : A critical evaluation. In: Investigative Radiology. 1989 ; Vol. 24, No. 12. pp. 1034-1038.
@article{0c95255c3ae34764bbf17fdb6aa3ad22,
title = "Clinical magnetic resonance spectroscopy: A critical evaluation",
abstract = "The present status of magnetic resonance spectroscopy (MRS) in the clinical radiology setting is discussed critically. The number of groups reporting clinical MRS results has increased, indicating the feasibility of performing localized MRS studies on current 1.5 T whole body MR imagers. However the lack of high quality radiofrequency (RF) coils for MRS and proven user-independent methods for the analysis of spectral data is still hampering further development. At present there is no consensus as to the optimal localization scheme which should be employed for phosphorus (31P) MRS. For proton MRS the stimulated echo sequence is gaining wide acceptance. The minimum voxel sizes achievable for proton and 31P MRS in the brain are calculated to be 2 and 30 cm3, respectively. The recent results obtained with proton decoupling for 31P clearly demonstrate that there is a great deal of improvement possible in the quality of localized 31P spectra at 1.5 T. Both the instrument manufacturers and researchers in the field face important challenges in translating methods which have proven feasibility in the research environment into routine clinical protocols.",
keywords = "clinical, magnetic, resonance, spectroscopy",
author = "Lenkinski, {R. E.}",
year = "1989",
language = "English (US)",
volume = "24",
pages = "1034--1038",
journal = "Investigative Radiology",
issn = "0020-9996",
publisher = "Lippincott Williams and Wilkins",
number = "12",

}

TY - JOUR

T1 - Clinical magnetic resonance spectroscopy

T2 - A critical evaluation

AU - Lenkinski, R. E.

PY - 1989

Y1 - 1989

N2 - The present status of magnetic resonance spectroscopy (MRS) in the clinical radiology setting is discussed critically. The number of groups reporting clinical MRS results has increased, indicating the feasibility of performing localized MRS studies on current 1.5 T whole body MR imagers. However the lack of high quality radiofrequency (RF) coils for MRS and proven user-independent methods for the analysis of spectral data is still hampering further development. At present there is no consensus as to the optimal localization scheme which should be employed for phosphorus (31P) MRS. For proton MRS the stimulated echo sequence is gaining wide acceptance. The minimum voxel sizes achievable for proton and 31P MRS in the brain are calculated to be 2 and 30 cm3, respectively. The recent results obtained with proton decoupling for 31P clearly demonstrate that there is a great deal of improvement possible in the quality of localized 31P spectra at 1.5 T. Both the instrument manufacturers and researchers in the field face important challenges in translating methods which have proven feasibility in the research environment into routine clinical protocols.

AB - The present status of magnetic resonance spectroscopy (MRS) in the clinical radiology setting is discussed critically. The number of groups reporting clinical MRS results has increased, indicating the feasibility of performing localized MRS studies on current 1.5 T whole body MR imagers. However the lack of high quality radiofrequency (RF) coils for MRS and proven user-independent methods for the analysis of spectral data is still hampering further development. At present there is no consensus as to the optimal localization scheme which should be employed for phosphorus (31P) MRS. For proton MRS the stimulated echo sequence is gaining wide acceptance. The minimum voxel sizes achievable for proton and 31P MRS in the brain are calculated to be 2 and 30 cm3, respectively. The recent results obtained with proton decoupling for 31P clearly demonstrate that there is a great deal of improvement possible in the quality of localized 31P spectra at 1.5 T. Both the instrument manufacturers and researchers in the field face important challenges in translating methods which have proven feasibility in the research environment into routine clinical protocols.

KW - clinical

KW - magnetic

KW - resonance

KW - spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=0024834590&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024834590&partnerID=8YFLogxK

M3 - Article

C2 - 2606632

AN - SCOPUS:0024834590

VL - 24

SP - 1034

EP - 1038

JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 12

ER -