TY - JOUR
T1 - Clinical practice guidelines for oral management of Sjögren disease
T2 - Dental caries prevention
AU - Zero, Domenick T.
AU - Brennan, Michael T.
AU - Daniels, Troy E.
AU - Papas, Athena
AU - Stewart, Carol
AU - Pinto, Andres
AU - Al-Hashimi, Ibtisam
AU - Navazesh, Mahvash
AU - Rhodus, Nelson
AU - Sciubba, James
AU - Singh, Mabi
AU - Wu, Ava J.
AU - Frantsve-Hawley, Julie
AU - Tracy, Sharon
AU - Fox, Philip C.
AU - Ford, Theresa Lawrence
AU - Cohen, Stephen
AU - Vivino, Frederick B.
AU - Hammitt, Katherine M.
N1 - Publisher Copyright:
© 2016 American Dental Association. All rights reserved.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Background Salivary dysfunction in Sjögren disease can lead to serious and costly oral health complications. Clinical practice guidelines for caries prevention in Sjögren disease were developed to improve quality and consistency of care. Methods A national panel of experts devised clinical questions in a Population, Intervention, Comparison, Outcomes format and included use of fluoride, salivary stimulants, antimicrobial agents, and nonfluoride remineralizing agents. The panel conducted a systematic search of the literature according to pre-established parameters. At least 2 members extracted the data, and the panel rated the strength of the recommendations by using a variation of grading of recommendations, assessment, development, and evaluation. After a Delphi consensus panel was conducted, the experts finalized the recommendations, with a minimum of 75% agreement required. Results Final recommendations for patients with Sjögren disease with dry mouth were as follows: topical fluoride should be used in all patients (strong); although no study results link improved salivary flow to caries prevention, the oral health community generally accepts that increasing saliva may contribute to decreased caries incidence, so increasing saliva through gustatory, masticatory, or pharmaceutical stimulation may be considered (weak); chlorhexidine administered as varnish, gel, or rinse may be considered (weak); and nonfluoride remineralizing agents may be considered as an adjunct therapy (moderate). Conclusions and Practical Implications The incidence of caries in patients with Sjögren disease can be reduced with the use of topical fluoride and other preventive strategies.
AB - Background Salivary dysfunction in Sjögren disease can lead to serious and costly oral health complications. Clinical practice guidelines for caries prevention in Sjögren disease were developed to improve quality and consistency of care. Methods A national panel of experts devised clinical questions in a Population, Intervention, Comparison, Outcomes format and included use of fluoride, salivary stimulants, antimicrobial agents, and nonfluoride remineralizing agents. The panel conducted a systematic search of the literature according to pre-established parameters. At least 2 members extracted the data, and the panel rated the strength of the recommendations by using a variation of grading of recommendations, assessment, development, and evaluation. After a Delphi consensus panel was conducted, the experts finalized the recommendations, with a minimum of 75% agreement required. Results Final recommendations for patients with Sjögren disease with dry mouth were as follows: topical fluoride should be used in all patients (strong); although no study results link improved salivary flow to caries prevention, the oral health community generally accepts that increasing saliva may contribute to decreased caries incidence, so increasing saliva through gustatory, masticatory, or pharmaceutical stimulation may be considered (weak); chlorhexidine administered as varnish, gel, or rinse may be considered (weak); and nonfluoride remineralizing agents may be considered as an adjunct therapy (moderate). Conclusions and Practical Implications The incidence of caries in patients with Sjögren disease can be reduced with the use of topical fluoride and other preventive strategies.
KW - Sjögren syndrome
KW - antimicrobial
KW - fluoride
KW - practice guidelines
KW - remineralization
KW - salivary flow
KW - xerostomia
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U2 - 10.1016/j.adaj.2015.11.008
DO - 10.1016/j.adaj.2015.11.008
M3 - Article
C2 - 26762707
AN - SCOPUS:84952909709
SN - 0002-8177
VL - 147
SP - 295
EP - 305
JO - Journal of the American Dental Association
JF - Journal of the American Dental Association
IS - 4
ER -