CLIPPERS associated with hypersensitivity pneumonitis: a case report

Maria Andrea Parra Corral, Jose Gavito-Higuera, Thomas O'Neill, Sajeev R.Ezhapilli Chennan

Research output: Contribution to journalArticlepeer-review

Abstract

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare and poorly understood pathology. In this case report we present a 51-year-old male that presented with neurological deficits with recent hypersensitivity pneumonitis. Imaging studies showed multiple punctate enhancing lesions involving the brainstem. After initiation of corticosteroids his symptoms improved, with a decrease in size of his lesions 6-months after his initial presentation. Due to its misdiagnosis, we propose the use of diagnostic criteria, described on this case report, for prompt treatment to avoid neurological sequelae.

Original languageEnglish (US)
Pages (from-to)2411-2415
Number of pages5
JournalRadiology Case Reports
Volume16
Issue number9
DOIs
StatePublished - Sep 2021
Externally publishedYes

Keywords

  • Brain MRI
  • CLIPPERS
  • Hypersensitivity pneumonitis
  • Pons

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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