Cloning and characterization of the cDNA encoding mouse dipeptidyl peptidase I (Cathepsin C)

Michael J. McGuire, Peter E. Lipsky, Dwain L Thiele

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The mouse dipeptidyl peptidase I cDNA has been cloned and sequenced and patterns of DPPI mRNA expression in various tissues characterized. Sequences encoding DPPI are highly conserved among mouse, rat and human and include an unusually long propeptide and a distinctive tyrosine adjacent to the active site cysteine.

Original languageEnglish (US)
Pages (from-to)267-273
Number of pages7
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1351
Issue number3
DOIs
StatePublished - Apr 10 1997

Fingerprint

Cathepsin C
Cloning
Cysteine
Tyrosine
Rats
Organism Cloning
Complementary DNA
Tissue
Messenger RNA
Catalytic Domain

Keywords

  • Cathepsin C
  • Cloning
  • Cysteine protease
  • Dipeptidyl peptidase I
  • Expression

ASJC Scopus subject areas

  • Biochemistry
  • Genetics
  • Structural Biology
  • Biophysics

Cite this

Cloning and characterization of the cDNA encoding mouse dipeptidyl peptidase I (Cathepsin C). / McGuire, Michael J.; Lipsky, Peter E.; Thiele, Dwain L.

In: Biochimica et Biophysica Acta - Gene Structure and Expression, Vol. 1351, No. 3, 10.04.1997, p. 267-273.

Research output: Contribution to journalArticle

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