Clopidogrel and coronary stents: Risks and benefits

Girish R. Mood, Anthony A. Bavry, Deepak L. Bhatt

Research output: Contribution to journalReview article

Abstract

Clopidogrel has become increasingly important in the management of patients with coronary stents. Clopidogrel is an oral agent that acts on the adenosine diphosphate receptor to irreversibly inhibit platelet aggregation. Along with aspirin, clopidogrel has a significant role in the treatment of atherothrombotic diseases. Recent concerns about late stent thrombosis highlight the need for long-term therapy with clopidogrel in addition to aspirin in these populations. This article reviews the role of clopidogrel in the treatment of atherothrombotic diseases and after coronary intervention, as well as the current approach in the prevention of stent thrombosis. It also discusses experimental and upcoming drugs that may be superior to clopidogrel.

Original languageEnglish (US)
Pages (from-to)303-308
Number of pages6
JournalCurrent atherosclerosis reports
Volume10
Issue number4
DOIs
StatePublished - Dec 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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