Abstract
An efficient radical transannulation reaction of pyridotriazoles with isothiocyanates and xanthate esters was developed. This method features conversion of pyridotriazoles into two N-fused heterocyclic aromatic systems-imino-thiazolopyridines and oxo-thiazolopyridine derivatives-via one-step Co(II)-catalyzed transannulation reaction proceeding via a radical mechanism. The synthetic usefulness of the developed method was illustrated in the synthesis of amino acid derivatives and further transformations of obtained reaction products.
Original language | English (US) |
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Pages (from-to) | 8500-8504 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 22 |
Issue number | 21 |
DOIs | |
State | Published - Nov 6 2020 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry