Co-Catalyzed Transannulation of Pyridotriazoles with Isothiocyanates and Xanthate Esters

Ziyan Zhang, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

An efficient radical transannulation reaction of pyridotriazoles with isothiocyanates and xanthate esters was developed. This method features conversion of pyridotriazoles into two N-fused heterocyclic aromatic systems-imino-thiazolopyridines and oxo-thiazolopyridine derivatives-via one-step Co(II)-catalyzed transannulation reaction proceeding via a radical mechanism. The synthetic usefulness of the developed method was illustrated in the synthesis of amino acid derivatives and further transformations of obtained reaction products.

Original languageEnglish (US)
Pages (from-to)8500-8504
Number of pages5
JournalOrganic Letters
Volume22
Issue number21
DOIs
StatePublished - Nov 6 2020
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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