Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles

Hai Huang, Hongdong Shi, Jing Liu, Yuanzeng Min, Yucai Wang, Andrew Z. Wang, Jun Wang, Yangzhong Liu

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Co-delivery of all-trans-retinoic acid and paclitaxel using albumin-bound nanoparticles demonstrated a significantly improved anti-metastatic effect to breast cancer both in vitro and in vivo. Notably, the co-delivery nanoparticles exhibited more pronounced therapeutic effects than the combination of two free drugs or two HSA loaded single drugs.

Original languageEnglish (US)
Pages (from-to)212-215
Number of pages4
JournalChemical Communications
Volume53
Issue number1
DOIs
StatePublished - 2017
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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