Coactivator control of cardiovascular growth and remodeling

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Transcriptional coactivators enhance gene expression by associating with sequence-specific transcription factors and serve as the primary targets of developmental and physiological signals in diverse biological processes. Recent studies have revealed key roles for transcriptional coactivators in the control of gene expression during development, growth and remodeling of the cardiovascular system. Based on the importance of the cardiovascular coactivators identified to date, coactivator control is emerging as a central regulatory mechanism in development and homeostasis of the cardiovascular system and other tissues.

Original languageEnglish (US)
Pages (from-to)715-722
Number of pages8
JournalCurrent Opinion in Cell Biology
Volume18
Issue number6
DOIs
StatePublished - Dec 1 2006

ASJC Scopus subject areas

  • Cell Biology

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