Cognition in relation to magnetic resonance imaging in head-injured children and adolescents

H. S. Levin, K. A. Culhane, D. Mendelsohn, M. A. Lilly, D. Bruce, J. M. Fletcher, S. B. Chapman, H. Harward, H. M. Eisenberg

Research output: Contribution to journalArticle

161 Citations (Scopus)

Abstract

To investigate the relationship between cognitive sequelae and magnetic resonance imaging (MRI) findings following closed head injury of varying severity in the pediatric age range, 76 head-injured children and adolescents were studied at least 3 months after trauma and compared with 57 normal controls. Problem solving, planning, verbal and design fluency, memory, and response modulation were assessed. Significant effects of injury were obtained on all of the cognitive measures. Cognitive impairment was more consistently present on the various outcome measures in children who were 6 to 10 years old at the time of the study than in the older children and adolescents. Magnetic resonance imaging disclosed areas of abnormal signal in the frontal lobes of 42 patients, whereas focal lesions restricted to the extrafrontal region were found in 15 children. Regression analyses disclosed that taking into account the size of frontal lobe lesion enhanced the relationship between cognitive performance and the severity of injury.

Original languageEnglish (US)
Pages (from-to)897-905
Number of pages9
JournalArchives of Neurology
Volume50
Issue number9
StatePublished - 1993

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Cognition
Head
Magnetic Resonance Imaging
Frontal Lobe
Wounds and Injuries
Closed Head Injuries
Time and Motion Studies
Regression Analysis
Outcome Assessment (Health Care)
Pediatrics
Lesion

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Levin, H. S., Culhane, K. A., Mendelsohn, D., Lilly, M. A., Bruce, D., Fletcher, J. M., ... Eisenberg, H. M. (1993). Cognition in relation to magnetic resonance imaging in head-injured children and adolescents. Archives of Neurology, 50(9), 897-905.

Cognition in relation to magnetic resonance imaging in head-injured children and adolescents. / Levin, H. S.; Culhane, K. A.; Mendelsohn, D.; Lilly, M. A.; Bruce, D.; Fletcher, J. M.; Chapman, S. B.; Harward, H.; Eisenberg, H. M.

In: Archives of Neurology, Vol. 50, No. 9, 1993, p. 897-905.

Research output: Contribution to journalArticle

Levin, HS, Culhane, KA, Mendelsohn, D, Lilly, MA, Bruce, D, Fletcher, JM, Chapman, SB, Harward, H & Eisenberg, HM 1993, 'Cognition in relation to magnetic resonance imaging in head-injured children and adolescents', Archives of Neurology, vol. 50, no. 9, pp. 897-905.
Levin HS, Culhane KA, Mendelsohn D, Lilly MA, Bruce D, Fletcher JM et al. Cognition in relation to magnetic resonance imaging in head-injured children and adolescents. Archives of Neurology. 1993;50(9):897-905.
Levin, H. S. ; Culhane, K. A. ; Mendelsohn, D. ; Lilly, M. A. ; Bruce, D. ; Fletcher, J. M. ; Chapman, S. B. ; Harward, H. ; Eisenberg, H. M. / Cognition in relation to magnetic resonance imaging in head-injured children and adolescents. In: Archives of Neurology. 1993 ; Vol. 50, No. 9. pp. 897-905.
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