Cognitive functional magnetic resonance imaging at very-high-field: Eye movement control

Beatriz Luna, John A. Sweeney

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The oculomotor system, which optimizes visual interaction with the environment, provides a valuable model system for probing the building blocks of higher-order cognition. Attention shifting, working memory, and inhibition of prepotent responses can be investigated in healthy individuals and patients with brain disorders. Although the neurophysiology of the oculomotor system has been well characterized at the single-cell level in nonhuman primates, its functional architecture in humans determined by evoked response procedures and studies of patients with focal lesions has been limited. Available evidence points to a widely distributed set of neocortical and subcortical brain regions involved in the control of eye movements, including brain stem, cerebellum, thalamus, striatum, and parietal and frontal cortices. The advent of functional magnetic resonance imaging provides a noninvasive manner of localizing, at high spatial resolution, the brain systems that subserve different aspects of sensory and cognitive processes in humans. Functional magnetic resonance imaging studies have already delineated the brain systems subserving sensorimotor and cognitive control of eye movements in adult and pediatric populations. Hence, the combination of functional magnetic resonance imaging and eye movement procedures can be used to probe the integrity of the brain in neurological and psychiatric disorders as well as provide a window into the changes in brain function subserving cognitive development.

Original languageEnglish (US)
Pages (from-to)3-15
Number of pages13
JournalTopics in Magnetic Resonance Imaging
Volume10
Issue number1
StatePublished - Feb 1999

Fingerprint

Eye Movements
Magnetic Resonance Imaging
Brain
Cognition
Parietal Lobe
Neurophysiology
Brain Diseases
Frontal Lobe
Nervous System Diseases
Thalamus
Short-Term Memory
Cerebellum
Primates
Brain Stem
Psychiatry
Pediatrics
Population

Keywords

  • Development
  • Eye movements
  • Frontal eye fields
  • Magnetic resonance imaging
  • Oculomotor system
  • Precentral sulcus
  • Supplementary eye fields

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Cognitive functional magnetic resonance imaging at very-high-field : Eye movement control. / Luna, Beatriz; Sweeney, John A.

In: Topics in Magnetic Resonance Imaging, Vol. 10, No. 1, 02.1999, p. 3-15.

Research output: Contribution to journalArticle

@article{7d3f738efb854b079d7ecf36f573d520,
title = "Cognitive functional magnetic resonance imaging at very-high-field: Eye movement control",
abstract = "The oculomotor system, which optimizes visual interaction with the environment, provides a valuable model system for probing the building blocks of higher-order cognition. Attention shifting, working memory, and inhibition of prepotent responses can be investigated in healthy individuals and patients with brain disorders. Although the neurophysiology of the oculomotor system has been well characterized at the single-cell level in nonhuman primates, its functional architecture in humans determined by evoked response procedures and studies of patients with focal lesions has been limited. Available evidence points to a widely distributed set of neocortical and subcortical brain regions involved in the control of eye movements, including brain stem, cerebellum, thalamus, striatum, and parietal and frontal cortices. The advent of functional magnetic resonance imaging provides a noninvasive manner of localizing, at high spatial resolution, the brain systems that subserve different aspects of sensory and cognitive processes in humans. Functional magnetic resonance imaging studies have already delineated the brain systems subserving sensorimotor and cognitive control of eye movements in adult and pediatric populations. Hence, the combination of functional magnetic resonance imaging and eye movement procedures can be used to probe the integrity of the brain in neurological and psychiatric disorders as well as provide a window into the changes in brain function subserving cognitive development.",
keywords = "Development, Eye movements, Frontal eye fields, Magnetic resonance imaging, Oculomotor system, Precentral sulcus, Supplementary eye fields",
author = "Beatriz Luna and Sweeney, {John A.}",
year = "1999",
month = "2",
language = "English (US)",
volume = "10",
pages = "3--15",
journal = "Topics in Magnetic Resonance Imaging",
issn = "0899-3459",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Cognitive functional magnetic resonance imaging at very-high-field

T2 - Eye movement control

AU - Luna, Beatriz

AU - Sweeney, John A.

PY - 1999/2

Y1 - 1999/2

N2 - The oculomotor system, which optimizes visual interaction with the environment, provides a valuable model system for probing the building blocks of higher-order cognition. Attention shifting, working memory, and inhibition of prepotent responses can be investigated in healthy individuals and patients with brain disorders. Although the neurophysiology of the oculomotor system has been well characterized at the single-cell level in nonhuman primates, its functional architecture in humans determined by evoked response procedures and studies of patients with focal lesions has been limited. Available evidence points to a widely distributed set of neocortical and subcortical brain regions involved in the control of eye movements, including brain stem, cerebellum, thalamus, striatum, and parietal and frontal cortices. The advent of functional magnetic resonance imaging provides a noninvasive manner of localizing, at high spatial resolution, the brain systems that subserve different aspects of sensory and cognitive processes in humans. Functional magnetic resonance imaging studies have already delineated the brain systems subserving sensorimotor and cognitive control of eye movements in adult and pediatric populations. Hence, the combination of functional magnetic resonance imaging and eye movement procedures can be used to probe the integrity of the brain in neurological and psychiatric disorders as well as provide a window into the changes in brain function subserving cognitive development.

AB - The oculomotor system, which optimizes visual interaction with the environment, provides a valuable model system for probing the building blocks of higher-order cognition. Attention shifting, working memory, and inhibition of prepotent responses can be investigated in healthy individuals and patients with brain disorders. Although the neurophysiology of the oculomotor system has been well characterized at the single-cell level in nonhuman primates, its functional architecture in humans determined by evoked response procedures and studies of patients with focal lesions has been limited. Available evidence points to a widely distributed set of neocortical and subcortical brain regions involved in the control of eye movements, including brain stem, cerebellum, thalamus, striatum, and parietal and frontal cortices. The advent of functional magnetic resonance imaging provides a noninvasive manner of localizing, at high spatial resolution, the brain systems that subserve different aspects of sensory and cognitive processes in humans. Functional magnetic resonance imaging studies have already delineated the brain systems subserving sensorimotor and cognitive control of eye movements in adult and pediatric populations. Hence, the combination of functional magnetic resonance imaging and eye movement procedures can be used to probe the integrity of the brain in neurological and psychiatric disorders as well as provide a window into the changes in brain function subserving cognitive development.

KW - Development

KW - Eye movements

KW - Frontal eye fields

KW - Magnetic resonance imaging

KW - Oculomotor system

KW - Precentral sulcus

KW - Supplementary eye fields

UR - http://www.scopus.com/inward/record.url?scp=0032999490&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032999490&partnerID=8YFLogxK

M3 - Article

C2 - 10389669

AN - SCOPUS:0032999490

VL - 10

SP - 3

EP - 15

JO - Topics in Magnetic Resonance Imaging

JF - Topics in Magnetic Resonance Imaging

SN - 0899-3459

IS - 1

ER -