Comb-type copolymers for controlled DNA delivery

A. Maruyama; A. Ferdous; T. Ishihara; S. Asayama; J. U. Park; M. Nogawa; H. Watanabe; Y. Takei; T. Akaike

doi:10.1080/07328319908044821

Comb-type copolymers for controlled DNA delivery

A. Maruyama, A. Ferdous, T. Ishihara, S. Asayama, J. U. Park, M. Nogawa, H. Watanabe, Y. Takei, T. Akaike

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Various comb-type copolymer containing a polycation as a main chain was design to construct delivery systems of DNAs. The comb-type copolymers having cell-specific polysaccharides were proved to be useful to deliver DNA to the target cells in vivo. Of interest, the copolymers with abundant side chains of hydrophilic polymers are capable of stabilizing DNA triplex. Further, injectable nanoparticles for controlled releases of DNAs were fabricated from the copolymer and a biodegradable polymer.

Original language	English (US)
Pages (from-to)	1681-1682
Number of pages	2
Journal	Nucleosides and Nucleotides
Volume	18
Issue number	6-7
DOIs	https://doi.org/10.1080/07328319908044821
State	Published - 1999

ASJC Scopus subject areas

Biochemistry
Genetics

Access to Document

10.1080/07328319908044821

Cite this

@article{a3e7acc226354d30a3d653d610c0d5fe,

title = "Comb-type copolymers for controlled DNA delivery",

abstract = "Various comb-type copolymer containing a polycation as a main chain was design to construct delivery systems of DNAs. The comb-type copolymers having cell-specific polysaccharides were proved to be useful to deliver DNA to the target cells in vivo. Of interest, the copolymers with abundant side chains of hydrophilic polymers are capable of stabilizing DNA triplex. Further, injectable nanoparticles for controlled releases of DNAs were fabricated from the copolymer and a biodegradable polymer.",

author = "A. Maruyama and A. Ferdous and T. Ishihara and S. Asayama and Park, {J. U.} and M. Nogawa and H. Watanabe and Y. Takei and T. Akaike",

year = "1999",

doi = "10.1080/07328319908044821",

language = "English (US)",

volume = "18",

pages = "1681--1682",

journal = "Nucleosides and Nucleotides",

issn = "0732-8311",

publisher = "Taylor and Francis Ltd.",

number = "6-7",

}

TY - JOUR

T1 - Comb-type copolymers for controlled DNA delivery

AU - Maruyama, A.

AU - Ferdous, A.

AU - Ishihara, T.

AU - Asayama, S.

AU - Park, J. U.

AU - Nogawa, M.

AU - Watanabe, H.

AU - Takei, Y.

AU - Akaike, T.

PY - 1999

Y1 - 1999

N2 - Various comb-type copolymer containing a polycation as a main chain was design to construct delivery systems of DNAs. The comb-type copolymers having cell-specific polysaccharides were proved to be useful to deliver DNA to the target cells in vivo. Of interest, the copolymers with abundant side chains of hydrophilic polymers are capable of stabilizing DNA triplex. Further, injectable nanoparticles for controlled releases of DNAs were fabricated from the copolymer and a biodegradable polymer.

AB - Various comb-type copolymer containing a polycation as a main chain was design to construct delivery systems of DNAs. The comb-type copolymers having cell-specific polysaccharides were proved to be useful to deliver DNA to the target cells in vivo. Of interest, the copolymers with abundant side chains of hydrophilic polymers are capable of stabilizing DNA triplex. Further, injectable nanoparticles for controlled releases of DNAs were fabricated from the copolymer and a biodegradable polymer.

UR - http://www.scopus.com/inward/record.url?scp=0032795360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032795360&partnerID=8YFLogxK

U2 - 10.1080/07328319908044821

DO - 10.1080/07328319908044821

M3 - Article

C2 - 10474245

AN - SCOPUS:0032795360

SN - 0732-8311

VL - 18

SP - 1681

EP - 1682

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 6-7

ER -

Comb-type copolymers for controlled DNA delivery

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this