TY - JOUR
T1 - Combating high-priority biological agents
T2 - What to do with drug-allergic patients and those for whom vaccination is contraindicated?
AU - Gruchalla, Rebecca S.
AU - Jones, James
PY - 2003/10/1
Y1 - 2003/10/1
N2 - The threat of bioterrorism continues to be a very real one. Regularly, there are news stories on bioterrorism-related topics: What biologic weapons will our enemies likely use to attack the United States? How prepared is our country to successfully counter such attacks? Although these critical questions are being addressed by the leaders of our country, allergists-immunologists, too, will have to grapple with difficult questions during these uncertain and frightening times. We care for a special group of patients with various allergic and immunologic disorders. Some of our patients have immunodeficiency disorders that might preclude them from receiving life-saving vaccines. Our patients with drug allergies are fearful that should they become infected with a biologic agent, they will not be able to receive appropriate treatment. In this article we focus on the various vaccine-related and antibiotic-related adverse effects that the allergist-immunologist might see during treatment of infections caused by Category A agents. Where possible, potential management approaches are outlined.
AB - The threat of bioterrorism continues to be a very real one. Regularly, there are news stories on bioterrorism-related topics: What biologic weapons will our enemies likely use to attack the United States? How prepared is our country to successfully counter such attacks? Although these critical questions are being addressed by the leaders of our country, allergists-immunologists, too, will have to grapple with difficult questions during these uncertain and frightening times. We care for a special group of patients with various allergic and immunologic disorders. Some of our patients have immunodeficiency disorders that might preclude them from receiving life-saving vaccines. Our patients with drug allergies are fearful that should they become infected with a biologic agent, they will not be able to receive appropriate treatment. In this article we focus on the various vaccine-related and antibiotic-related adverse effects that the allergist-immunologist might see during treatment of infections caused by Category A agents. Where possible, potential management approaches are outlined.
KW - Anthrax
KW - Antibiotic allergy
KW - Bioterrorism
KW - Botulism
KW - Category a biologic agents
KW - Plague
KW - Smallpox
KW - Vaccine-related adverse reactions
UR - http://www.scopus.com/inward/record.url?scp=0141956429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0141956429&partnerID=8YFLogxK
U2 - 10.1016/j.jaci.2003.08.001
DO - 10.1016/j.jaci.2003.08.001
M3 - Article
C2 - 14564343
AN - SCOPUS:0141956429
SN - 0091-6749
VL - 112
SP - 675
EP - 682
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
IS - 4
ER -