Combined acute myeloid leukemia and panhypopituitarism

Busara Songtanin, Tsuzumi Kanaoka, Joan Chandra, Sushela Chaidarun

Research output: Contribution to journalArticlepeer-review

Abstract

Panhypopituitarism is an extremely rare disorder in acute myeloid leukemia (AML). To our knowledge, only six cases have been reported. Of note, central diabetes insipidus is known to be associated with AML in patients with certain cytogenic abnormalities, such as monosomy chromosome 7 and inv(3)(q21;q26). We describe a 30-year-old incarcerated woman with newly diagnosed AML who developed panhypopituitarism. Her cytogenetic studies revealed a normal karyotype, were negative for inv(3)(q21;q26), but were positive for FMS-like tyrosine kinase 3 internal tandem duplication.

Original languageEnglish (US)
JournalBaylor University Medical Center Proceedings
DOIs
StateAccepted/In press - 2022
Externally publishedYes

Keywords

  • Acute myeloid leukemia
  • diabetes insipidus
  • panhypopituitarism

ASJC Scopus subject areas

  • Medicine(all)

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