Combined targeting of estrogen receptor alpha and XPO1 prevent AKT activation, remodel metabolic pathways and induce autophagy to overcome tamoxifen resistance

Eylem Kulkoyluoglu-Cotul, Brandi Patrice Smith, Kinga Wrobel, Yiru Chen Zhao, Karen Lee Ann Chen, Kadriye Hieronymi, Ozan Berk Imir, Kevin Duong, Caitlin O’Callaghan, Aditi Mehta, Sunati Sahoo, Barbara Haley, Hua Chang, Yosef Landesman, Zeynep Madak-Erdogan

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Medicine & Life Sciences