Comparative analysis of zymogen granule membrane polypeptides

Raymond J. MacDonald, Robert A. Ronzio

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Polypeptides of zymogen granule membranes from rat, beef, dog, pig, and rabbit pancreas were analyzed by polyacrylamide gel electrophoresis in 1% sodium dodecylsulfate. Granule membranes were characterized by a single major polypeptide species detected by the periodic acid-Schiff procedure. The relative mobilities of this component were similar for these mammals. The component was distinct from major polypeptides of mitochondrial or microsomal membranes. The zymogen granule membrane may, therefore, represent a highly specialized intracellular membrane.

Original languageEnglish (US)
Pages (from-to)377-382
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume49
Issue number2
DOIs
StatePublished - Oct 17 1972

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Enzyme Precursors
Secretory Vesicles
Membranes
Peptides
Intracellular Membranes
Periodic Acid
Beef
Mammals
Polyacrylamide Gel Electrophoresis
Pancreas
Electrophoresis
Swine
Sodium
Dogs
Rats
Rabbits

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Comparative analysis of zymogen granule membrane polypeptides. / MacDonald, Raymond J.; Ronzio, Robert A.

In: Biochemical and Biophysical Research Communications, Vol. 49, No. 2, 17.10.1972, p. 377-382.

Research output: Contribution to journalArticle

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