Chinese hamster x mouse somatic cell hybrids, segregating mouse chromosomes, were employed to investigate the extent of conservation of autosomal linkage groups between mouse and man. During this study, the linkage relationships and chromosomal assignment of mouse peptidase S (PEP-S, E.C. 3.4.11 ) were investigated. Evidence is presented here which indicates that the gene coding for PEP-S is located on mouse chromosome 5, and the significance of this gene assignment for comparative gene mapping is discussed.
ASJC Scopus subject areas
- Cell Biology