Comparative pharmacokinetics of cyclacillin and amoxicillin in infants and children

C. M. Ginsburg, G. H. McCracken, T. C. Zweighaft, J. C. Clahsen

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Concentrations of cyclacillin in serum over a 6-h period were similar in fasted and milk-fed infants who received 25-mg/kg dose of cyclacillin suspension. Measured by the concentration in serum after oral administration of 15-mg/kg doses, cyclacillin was absorbed more rapidly, reached larger concentration, and was cleared more promptly than was amoxicillin.

Original languageEnglish (US)
Pages (from-to)1086-1088
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume19
Issue number6
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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