Comparing performance of the CADstream and the DynaCAD breast MRI CAD systems: CADstream vs. DynaCAD in breast MRI

Joann Pan, Basak E. Dogan, Selin Carkaci, Lumarie Santiago, Elsa Arribas, Scott B. Cantor, Wei Wei, R. Jason Stafford, Gary J. Whitman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Computer-aided diagnosis (CAD) systems are software programs that use algorithms to find patterns associated with breast cancer on breast magnetic resonance imaging (MRI). The most commonly used CAD systems in the USA are CADstream (CS) (Merge Healthcare Inc., Chicago, IL) and DynaCAD for Breast (DC) (Invivo, Gainesville, FL). Our primary objective in this study was to compare the CS and DC breast MRI CAD systems for diagnostic accuracy and postprocessed image quality. Our secondary objective was to compare the evaluation times of radiologists using each system. Three radiologists evaluated 30 biopsy-proven malignant lesions and 29 benign lesions on CS and DC and rated the lesions' malignancy status using the Breast Imaging Reporting and Data System. Image quality was ranked on a 0-5 scale, and mean reading times were also recorded. CS detected 70 % of the malignant and 32 % of the benign lesions while DC detected 81 % of the malignant lesions and 34 % of the benign lesions. Analysis of the area under the receiver operating characteristic curve revealed that the difference in diagnostic performance was not statistically significant. On image quality scores, CS had significantly higher volume rendering (VR) (p < 0.0001) and motion correction (MC) scores (p < 0.0001). There were no statistically significant differences in the remaining image quality scores. Differences in evaluation times between DC and CS were also not statistically significant. We conclude that both CS and DC perform similarly in aiding detection of breast cancer on MRI. MRI CAD selection will likely be based on other factors, such as user interface and image quality preferences, including MC and VR.

Original languageEnglish (US)
Pages (from-to)971-976
Number of pages6
JournalJournal of Digital Imaging
Volume26
Issue number5
DOIs
StatePublished - Oct 1 2013

Fingerprint

Computer aided diagnosis
Magnetic resonance
Image quality
Breast
Computer systems
Magnetic Resonance Imaging
Imaging techniques
Breast Neoplasms
Volume rendering
Information Systems
ROC Curve
Biopsy
Reading
Software
User interfaces
Delivery of Health Care
Neoplasms
Radiologists

Keywords

  • Breast
  • Breast diseases
  • Computer-aided diagnosis (CAD)
  • Computer-assisted detection
  • Diagnostic imaging
  • MR imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Science Applications

Cite this

Comparing performance of the CADstream and the DynaCAD breast MRI CAD systems : CADstream vs. DynaCAD in breast MRI. / Pan, Joann; Dogan, Basak E.; Carkaci, Selin; Santiago, Lumarie; Arribas, Elsa; Cantor, Scott B.; Wei, Wei; Stafford, R. Jason; Whitman, Gary J.

In: Journal of Digital Imaging, Vol. 26, No. 5, 01.10.2013, p. 971-976.

Research output: Contribution to journalArticle

Pan, J, Dogan, BE, Carkaci, S, Santiago, L, Arribas, E, Cantor, SB, Wei, W, Stafford, RJ & Whitman, GJ 2013, 'Comparing performance of the CADstream and the DynaCAD breast MRI CAD systems: CADstream vs. DynaCAD in breast MRI', Journal of Digital Imaging, vol. 26, no. 5, pp. 971-976. https://doi.org/10.1007/s10278-013-9602-y
Pan, Joann ; Dogan, Basak E. ; Carkaci, Selin ; Santiago, Lumarie ; Arribas, Elsa ; Cantor, Scott B. ; Wei, Wei ; Stafford, R. Jason ; Whitman, Gary J. / Comparing performance of the CADstream and the DynaCAD breast MRI CAD systems : CADstream vs. DynaCAD in breast MRI. In: Journal of Digital Imaging. 2013 ; Vol. 26, No. 5. pp. 971-976.
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