Comparison between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy

Qiao Yan Long, Qing Shan Chen, Yu Hua Chen, Jiao Liu, Yuanfei Zhu, Hai Lan Liao

Research output: Contribution to journalArticle

Abstract

AIM: To compare the curative effects between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. METHODS: Fifty patients with non-proliferative diabetic retinopathy from January 2010 to January 2014 in our hospital were selected for the study, and were divided into two groups, the control group and the observation group, using a random number table. Twenty-five patients (43 eyes) in the observation group completed panretinal photocoagulation (PRP) therapy once by 577nm laser multi-point scanning. Twenty-five patients (41 eyes) in the control group completed PRP therapy by the single-point multiple scanning. The differences of average threshold sensitivity of visual field, F-ERG a/b wave amplitude, the clinical effective rates, the laser energy, the number of laser spot and the energy density between the two groups at various time points were compared. RESULTS: At 1d after the treatments, average threshold sensitivity of visual field was lower than those at 1d before treament, and the difference was statistically significant (t=2.421, P=0.017). The differences of average threshold sensitivity between the two groups at 1d before treatments, at 1d, 1, 2, 6, 12mo after treatments, were not statistically significant (P>0.05). The F-ERG a wave amplitude of both groups at 1d after treatments were lower than those of 1d before treatments, and the difference was statistically significant (t=2.319, P=0.025). There were no differences of the F-ERG b wave amplitude between both groups at 1d before treatments and at 1d, 1, 2, 6, 12mo after treatments (P>0.05). The F-ERG b wave amplitude of both groups at 1d after treatments were lower than those at 1d before treatments, and the difference was statistically significant (t=2.276, P=0.031). There were no differences between the two groups in terms of clinical effective rates and the number of laser spot (P>0.05). Laser energy used in the observation group was higher than that in the control group, the energy density was lower than that in the control group. The differences on the two items were statistically significant (P <0.05). CONCLUSION: There is no significant difference on clinical efficacy between laser multi-point scanning and single-point multiple scanning of PRP therapy. But the energy density of multi-point scanning mode is lower, and the damage made by this mode is less.

Original languageEnglish (US)
Pages (from-to)1713-1716
Number of pages4
JournalInternational Eye Science
Volume15
Issue number10
DOIs
StatePublished - Oct 8 2015
Externally publishedYes

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Diabetic Retinopathy
Lasers
Light Coagulation
Therapeutics
Control Groups
Observation
Visual Fields

Keywords

  • 577nm laser multi-point scanning
  • Diabetic retinopathy
  • Non-proliferative phase
  • Single-point multiple scanning

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Comparison between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. / Long, Qiao Yan; Chen, Qing Shan; Chen, Yu Hua; Liu, Jiao; Zhu, Yuanfei; Liao, Hai Lan.

In: International Eye Science, Vol. 15, No. 10, 08.10.2015, p. 1713-1716.

Research output: Contribution to journalArticle

Long, Qiao Yan ; Chen, Qing Shan ; Chen, Yu Hua ; Liu, Jiao ; Zhu, Yuanfei ; Liao, Hai Lan. / Comparison between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. In: International Eye Science. 2015 ; Vol. 15, No. 10. pp. 1713-1716.
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title = "Comparison between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy",
abstract = "AIM: To compare the curative effects between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. METHODS: Fifty patients with non-proliferative diabetic retinopathy from January 2010 to January 2014 in our hospital were selected for the study, and were divided into two groups, the control group and the observation group, using a random number table. Twenty-five patients (43 eyes) in the observation group completed panretinal photocoagulation (PRP) therapy once by 577nm laser multi-point scanning. Twenty-five patients (41 eyes) in the control group completed PRP therapy by the single-point multiple scanning. The differences of average threshold sensitivity of visual field, F-ERG a/b wave amplitude, the clinical effective rates, the laser energy, the number of laser spot and the energy density between the two groups at various time points were compared. RESULTS: At 1d after the treatments, average threshold sensitivity of visual field was lower than those at 1d before treament, and the difference was statistically significant (t=2.421, P=0.017). The differences of average threshold sensitivity between the two groups at 1d before treatments, at 1d, 1, 2, 6, 12mo after treatments, were not statistically significant (P>0.05). The F-ERG a wave amplitude of both groups at 1d after treatments were lower than those of 1d before treatments, and the difference was statistically significant (t=2.319, P=0.025). There were no differences of the F-ERG b wave amplitude between both groups at 1d before treatments and at 1d, 1, 2, 6, 12mo after treatments (P>0.05). The F-ERG b wave amplitude of both groups at 1d after treatments were lower than those at 1d before treatments, and the difference was statistically significant (t=2.276, P=0.031). There were no differences between the two groups in terms of clinical effective rates and the number of laser spot (P>0.05). Laser energy used in the observation group was higher than that in the control group, the energy density was lower than that in the control group. The differences on the two items were statistically significant (P <0.05). CONCLUSION: There is no significant difference on clinical efficacy between laser multi-point scanning and single-point multiple scanning of PRP therapy. But the energy density of multi-point scanning mode is lower, and the damage made by this mode is less.",
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T1 - Comparison between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy

AU - Long, Qiao Yan

AU - Chen, Qing Shan

AU - Chen, Yu Hua

AU - Liu, Jiao

AU - Zhu, Yuanfei

AU - Liao, Hai Lan

PY - 2015/10/8

Y1 - 2015/10/8

N2 - AIM: To compare the curative effects between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. METHODS: Fifty patients with non-proliferative diabetic retinopathy from January 2010 to January 2014 in our hospital were selected for the study, and were divided into two groups, the control group and the observation group, using a random number table. Twenty-five patients (43 eyes) in the observation group completed panretinal photocoagulation (PRP) therapy once by 577nm laser multi-point scanning. Twenty-five patients (41 eyes) in the control group completed PRP therapy by the single-point multiple scanning. The differences of average threshold sensitivity of visual field, F-ERG a/b wave amplitude, the clinical effective rates, the laser energy, the number of laser spot and the energy density between the two groups at various time points were compared. RESULTS: At 1d after the treatments, average threshold sensitivity of visual field was lower than those at 1d before treament, and the difference was statistically significant (t=2.421, P=0.017). The differences of average threshold sensitivity between the two groups at 1d before treatments, at 1d, 1, 2, 6, 12mo after treatments, were not statistically significant (P>0.05). The F-ERG a wave amplitude of both groups at 1d after treatments were lower than those of 1d before treatments, and the difference was statistically significant (t=2.319, P=0.025). There were no differences of the F-ERG b wave amplitude between both groups at 1d before treatments and at 1d, 1, 2, 6, 12mo after treatments (P>0.05). The F-ERG b wave amplitude of both groups at 1d after treatments were lower than those at 1d before treatments, and the difference was statistically significant (t=2.276, P=0.031). There were no differences between the two groups in terms of clinical effective rates and the number of laser spot (P>0.05). Laser energy used in the observation group was higher than that in the control group, the energy density was lower than that in the control group. The differences on the two items were statistically significant (P <0.05). CONCLUSION: There is no significant difference on clinical efficacy between laser multi-point scanning and single-point multiple scanning of PRP therapy. But the energy density of multi-point scanning mode is lower, and the damage made by this mode is less.

AB - AIM: To compare the curative effects between laser multi-point scanning and single-point multiple scanning for the treatment of non-proliferative diabetic retinopathy. METHODS: Fifty patients with non-proliferative diabetic retinopathy from January 2010 to January 2014 in our hospital were selected for the study, and were divided into two groups, the control group and the observation group, using a random number table. Twenty-five patients (43 eyes) in the observation group completed panretinal photocoagulation (PRP) therapy once by 577nm laser multi-point scanning. Twenty-five patients (41 eyes) in the control group completed PRP therapy by the single-point multiple scanning. The differences of average threshold sensitivity of visual field, F-ERG a/b wave amplitude, the clinical effective rates, the laser energy, the number of laser spot and the energy density between the two groups at various time points were compared. RESULTS: At 1d after the treatments, average threshold sensitivity of visual field was lower than those at 1d before treament, and the difference was statistically significant (t=2.421, P=0.017). The differences of average threshold sensitivity between the two groups at 1d before treatments, at 1d, 1, 2, 6, 12mo after treatments, were not statistically significant (P>0.05). The F-ERG a wave amplitude of both groups at 1d after treatments were lower than those of 1d before treatments, and the difference was statistically significant (t=2.319, P=0.025). There were no differences of the F-ERG b wave amplitude between both groups at 1d before treatments and at 1d, 1, 2, 6, 12mo after treatments (P>0.05). The F-ERG b wave amplitude of both groups at 1d after treatments were lower than those at 1d before treatments, and the difference was statistically significant (t=2.276, P=0.031). There were no differences between the two groups in terms of clinical effective rates and the number of laser spot (P>0.05). Laser energy used in the observation group was higher than that in the control group, the energy density was lower than that in the control group. The differences on the two items were statistically significant (P <0.05). CONCLUSION: There is no significant difference on clinical efficacy between laser multi-point scanning and single-point multiple scanning of PRP therapy. But the energy density of multi-point scanning mode is lower, and the damage made by this mode is less.

KW - 577nm laser multi-point scanning

KW - Diabetic retinopathy

KW - Non-proliferative phase

KW - Single-point multiple scanning

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