TY - JOUR
T1 - Comparison between the analgesic efficacy of transversus abdominis plane (TAP) block and placebo in open retropubic radical prostatectomy
T2 - A prospective, randomized, double-blinded study
AU - Elkassabany, Nabil
AU - Ahmed, Moustafa
AU - Malkowicz, S. Bruce
AU - Heitjan, Daniel F.
AU - Isserman, Joshua A.
AU - Ochroch, E. Andrew
PY - 2013/9
Y1 - 2013/9
N2 - Study Objective To compare the efficacy of ultrasound-guided tansversus abdominis plane (TAP) block with placebo for postoperative analgesia after retropubic radical prostatectomy (RRP). Design Prospective, randomized, double-blinded study. Setting Tertiary-care Veterans Affairs (VA) hospital. Patients ASA physical status 1, 2, and 3 patients scheduled for RRP. Interventions Patients were randomized to two groups: the TAP group and the control group. All patients underwent an ultrasound-guided TAP block procedure after induction of general anesthesia and received either local anesthetic (TAP group) or normal saline (control group). Measurements Opioid use and verbal analog pain scores at 1, 6, 12, and 24 hours after surgery were recorded, as was the frequency of side effects. Times to ambulation and first oral intake also were recorded. Main Results The TAP block group had lower pain scores and required less total opioid in the first 24 hours after surgery. Time to first oral intake and time to ambulation were similar between the two groups. Conclusion The TAP block has early benefits in postoperative analgesia after RRP.
AB - Study Objective To compare the efficacy of ultrasound-guided tansversus abdominis plane (TAP) block with placebo for postoperative analgesia after retropubic radical prostatectomy (RRP). Design Prospective, randomized, double-blinded study. Setting Tertiary-care Veterans Affairs (VA) hospital. Patients ASA physical status 1, 2, and 3 patients scheduled for RRP. Interventions Patients were randomized to two groups: the TAP group and the control group. All patients underwent an ultrasound-guided TAP block procedure after induction of general anesthesia and received either local anesthetic (TAP group) or normal saline (control group). Measurements Opioid use and verbal analog pain scores at 1, 6, 12, and 24 hours after surgery were recorded, as was the frequency of side effects. Times to ambulation and first oral intake also were recorded. Main Results The TAP block group had lower pain scores and required less total opioid in the first 24 hours after surgery. Time to first oral intake and time to ambulation were similar between the two groups. Conclusion The TAP block has early benefits in postoperative analgesia after RRP.
KW - Patient-controlled analgesia
KW - Peripheral nerve block
KW - Postoperative analgesia
KW - Regional anesthesia
KW - Retropubic radical prostatectomy (RRP)
KW - Transversus abdominis plane (TAP) block
KW - Urological surgery
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U2 - 10.1016/j.jclinane.2013.04.009
DO - 10.1016/j.jclinane.2013.04.009
M3 - Article
C2 - 23965191
AN - SCOPUS:84887023673
SN - 0952-8180
VL - 25
SP - 459
EP - 465
JO - Journal of Clinical Anesthesia
JF - Journal of Clinical Anesthesia
IS - 6
ER -