Abstract
In a double-blind randomized clinical trial co-trimazine was compared with co-trimoxazole in 212 patients with urinary tract infections. Co-trimazine (TMP 180 mg plus SMZ 820 mg) was given once daily and co-trimoxazole (TMP 160 mg plus SMZ 800 mg) twice daily. 14 to 21 days after the end of treatment the bacteriological cure rate was 90% for co-trimazine and 87% for co-trimoxazole. Bacterial resistance was only observed in a few cases. Side-effects occurred in 11.7% of the patients treated with co-trimazine and in 15.4% of those treated with co-trimoxazole. The side-effects were generally mild and only once in each regimen was treatment discontinued.
| Translated title of the contribution | Comparison of co-trimazine and co-trimoxazole in urinary tract infections |
|---|---|
| Original language | German |
| Pages (from-to) | 6596-6603 |
| Number of pages | 8 |
| Journal | Therapiewoche |
| Volume | 34 |
| Issue number | 46 |
| State | Published - Jan 1 1984 |
ASJC Scopus subject areas
- Pharmacology