Comparison of indices allowing an evaluation of detrusor contractility in women

F. A. Valentini, B. G. Marti, G. Robain, P. E. Zimern, P. P. Nelson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Aims: To compare 3 detrusor contractility indices, projected isovolumetric pressure (PIP-BCI), PIP1, and k from the VBN mathematical model, for women referred for evaluation of various lower urinary tract symptoms (LUTS) in relationship to age, presenting complaint and urodynamic diagnosis. Methods: Urodynamic tracings of non-neurologic women were analyzed. Three indices of detrusor contractility were measured from the pressure-flow study. Exclusion criteria were voided volume < 100 mL, stage > 2 prolapse, interrupted flow, abdominal straining. Age sub-groups were pre-, peri- and post-menopause. Urodynamic diagnosis included incontinence findings and detrusor activity during voiding. Results: Main complaint was incontinence (354 women); 95 women (Other) had non-incontinence LUTS. PIP-BCI, PIP1 and k decreased significantly with ageing in each sub-group. PIP-BCI was significantly different between MUI and Other (P =.0259) while PIP1 was significantly higher in UUI vs. Other (P =.0161) and k in UUI vs. SUI (P =.0107), MUI (P =.0010) and Other (P =.0224). Low value of PIP-BCI for bladder outlet obstruction vs. detrusor overactivity while PIP1 and k values were high and similar for these two diagnoses and a high value of PIP-BCI for detrusor overactivity with impaired contractility close to the value for bladder outlet obstruction while PIP1 and k were low. Conclusion: Evaluation of detrusor contractility in women is easily obtained using indices PIP-BCI and PIP1 or using the VBN nomogram giving indice-parameter k. PIP1 and parameter k produced comparable and consistent results with the urodynamic diagnosis while PIP-BCI leads to inconsistencies. Level of evidence: 4.

Original languageEnglish (US)
Pages (from-to)396-401
Number of pages6
JournalProgres en Urologie
Volume30
Issue number7
DOIs
StatePublished - Jun 2020

Keywords

  • Contractilité du détrusor
  • Detrusor contractility indices
  • Femme
  • Index de contractilité
  • Urodynamics
  • Urodynamique
  • Woman

ASJC Scopus subject areas

  • Urology

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