Comparison of Iodixanol and Ioxaglate for Coronary Optical Coherence Tomography Imaging

Georgios E. Christakopoulos, Anna P. Kotsia, Georgios Christopoulos, Shuaib M. Abdullah, Bavana V. Rangan, Michele Roesle, Subhash Banerjee, Emmanouil S. Brilakis

Research output: Contribution to journalArticle

Abstract

BACKGROUND: The impact of contrast type on coronary imaging using optical coherence tomography (OCT) has received limited study. We compared OCT imaging obtained using the non-ionic, iso-osmolar iodixanol with the ionic, low-osmolar ioxaglate. METHODS: Twenty-two vessels in 20 patients were imaged twice using manual injection of iodixanol and ioxaglate in random order. OCT images were analyzed at 1 mm intervals to determine lumen area, artifact diameter and area, as well as stent strut coverage and malapposition in OCT pullbacks that included stents. RESULTS: There were no complications related to OCT imaging or to contrast administration. A total of 2184 cross-sections (1092 with iodixanol and 1092 with ioxaglate) were analyzed. Compared with iodixanol, imaging using ioxaglate provided similar mean lumen area (6.21 ± 2.83 mm2 vs 6.27 ± 2.83 mm2; Spearman's rho, 0.982), mean minimum lumen diameter (2.47 ± 0.59 mm vs 2.50 ± 0.58 mm; Spearman's rho, 0.939), and mean maximum lumen diameter (2.99 ± 0.71 mm vs 3.01 ± 0.70 mm; Spearman's rho, 0.964), but lower mean artifact area per cross-section (0.099 ± 0.325 mm2 vs 0.068 ± 0.329 mm2; P

Original languageEnglish (US)
Pages (from-to)E287-E290
JournalJournal of Invasive Cardiology
Volume27
Issue number12
StatePublished - Dec 1 2015

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Ioxaglic Acid
Optical Coherence Tomography
Artifacts
Stents
iodixanol
Injections

Keywords

  • cardiac imaging
  • coronary artery disease
  • iodixanol
  • ioxaglate
  • radiographic contrast

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Comparison of Iodixanol and Ioxaglate for Coronary Optical Coherence Tomography Imaging. / Christakopoulos, Georgios E.; Kotsia, Anna P.; Christopoulos, Georgios; Abdullah, Shuaib M.; Rangan, Bavana V.; Roesle, Michele; Banerjee, Subhash; Brilakis, Emmanouil S.

In: Journal of Invasive Cardiology, Vol. 27, No. 12, 01.12.2015, p. E287-E290.

Research output: Contribution to journalArticle

Christakopoulos GE, Kotsia AP, Christopoulos G, Abdullah SM, Rangan BV, Roesle M et al. Comparison of Iodixanol and Ioxaglate for Coronary Optical Coherence Tomography Imaging. Journal of Invasive Cardiology. 2015 Dec 1;27(12):E287-E290.
Christakopoulos, Georgios E. ; Kotsia, Anna P. ; Christopoulos, Georgios ; Abdullah, Shuaib M. ; Rangan, Bavana V. ; Roesle, Michele ; Banerjee, Subhash ; Brilakis, Emmanouil S. / Comparison of Iodixanol and Ioxaglate for Coronary Optical Coherence Tomography Imaging. In: Journal of Invasive Cardiology. 2015 ; Vol. 27, No. 12. pp. E287-E290.
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