TY - JOUR
T1 - Comparison of quality of life measures in a depressed population
AU - Wisniewski, Stephen R.
AU - Rush, A. John
AU - Bryan, Charlene
AU - Shelton, Richard
AU - Trivedi, Madhukar H.
AU - Marcus, Sheila
AU - Husain, Mustafa M.
AU - Hollon, Steven D.
AU - Fava, Maurizio
PY - 2007/3
Y1 - 2007/3
N2 - Measures of quality of life have been increasingly used in clinical trials. When designing a study, researchers must decide which quality of life measure to use. Some literature provides guidance through general recommendations, though lacks quantitative comparisons. In this report, 2 general quality of life measures, the 12-Item Short Form Health Survey (SF-12) and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), are compared in a depressed population. STAR*D data were used to analyze the associations among the SF-12 and the Q-LES-Q. Each measure covers 6 domains, overlapping on 5 (health, self-esteem/well-being, community/productivity, social/love relationships, leisure/creativity), with the SF-12 addressing family and the Q-LES-Q addressing living situations. Strong item-by-item associations exist only between the Q-LES-Q and the SF-12 physical health items. The 2 measures overlap on the domains covered while the lack of correlation between the 2 measures may be attributed to the perspective of each question as the Q-LES-Q measures satisfaction while the SF-12 measures the patient's perception of function.
AB - Measures of quality of life have been increasingly used in clinical trials. When designing a study, researchers must decide which quality of life measure to use. Some literature provides guidance through general recommendations, though lacks quantitative comparisons. In this report, 2 general quality of life measures, the 12-Item Short Form Health Survey (SF-12) and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), are compared in a depressed population. STAR*D data were used to analyze the associations among the SF-12 and the Q-LES-Q. Each measure covers 6 domains, overlapping on 5 (health, self-esteem/well-being, community/productivity, social/love relationships, leisure/creativity), with the SF-12 addressing family and the Q-LES-Q addressing living situations. Strong item-by-item associations exist only between the Q-LES-Q and the SF-12 physical health items. The 2 measures overlap on the domains covered while the lack of correlation between the 2 measures may be attributed to the perspective of each question as the Q-LES-Q measures satisfaction while the SF-12 measures the patient's perception of function.
KW - Depression
KW - Function
KW - Quality of life
KW - Satisfaction
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U2 - 10.1097/01.nmd.0000258229.38212.6f
DO - 10.1097/01.nmd.0000258229.38212.6f
M3 - Article
C2 - 17468681
AN - SCOPUS:34247602115
SN - 0022-3018
VL - 195
SP - 219
EP - 225
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
IS - 3
ER -