Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology guidelines for the management of patients with non-ST-segment elevation acute coronary syndromes

Aya J. Alame, Aris Karatasakis, Judit Karacsonyi, Barbara A. Danek, Erica Resendes, Jose R. Martinez Parachini, Pratik Kalsaria, Michele Roesle, Bavana V. Rangan, Paul Sorajja, Hani Jneid, Subhash Banerjee, Emmanouil S. Brilakis

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

INTRODUCTION: The American College of Cardiology (ACC), the American Heart Association (AHA), and the European Society of Cardiology (ESC) have been developing guidelines to assist clinicians in making evidence-based decisions. MATERIALS AND METHODS: The current ACC/AHA and ESC guidelines for non-ST-segment elevation acute coronary syndromes (NSTE-ACS) that were updated in 2014 and 2015, respectively, were compared to assess the number of recommendations on the basis of class of recommendation and level of evidence (LOE), the sources cited, and the content. RESULTS: The total number of recommendations in the ACC/AHA and ESC guidelines was 182 and 147, respectively. The recommendation class distribution of the ACC/AHA guidelines was 61.0% class I (compared with 61.9% in the ESC guidelines, P=0.865), 29.7% class II (compared with 32.0% in the ESC guidelines, P=0.653), and 9.3% class III (compared with 6.1% in the ESC guidelines, P=0.282). The LOE distribution among ACC/AHA guidelines was 15.9% LOE A (compared with 27.9% in the ESC guidelines, P=0.008), 50.0% LOE B (compared with 33.3% in the ESC guidelines, P=0.002), and 34.1% LOE C (compared with 38.8% in the ESC guidelines, P=0.377). The ACC/AHA guidelines cited 827 publications and the ESC guidelines cited 551 publications, 124 of which were shared by both sets of guidelines. The guidelines’ approaches to NSTE-ACS were consistent, with minor differences in diagnostic and medical therapy recommendations. CONCLUSION: Overall, the ACC/AHA and ESC guidelines contain a comparable number of recommendations and provide similar guidance for the management of patients with NSTE-ACS.

Original languageEnglish (US)
JournalCoronary Artery Disease
DOIs
StateAccepted/In press - Mar 16 2017

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Acute Coronary Syndrome
Cardiology
Guidelines
American Heart Association
Publications

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology guidelines for the management of patients with non-ST-segment elevation acute coronary syndromes. / Alame, Aya J.; Karatasakis, Aris; Karacsonyi, Judit; Danek, Barbara A.; Resendes, Erica; Martinez Parachini, Jose R.; Kalsaria, Pratik; Roesle, Michele; Rangan, Bavana V.; Sorajja, Paul; Jneid, Hani; Banerjee, Subhash; Brilakis, Emmanouil S.

In: Coronary Artery Disease, 16.03.2017.

Research output: Contribution to journalArticle

Alame, Aya J. ; Karatasakis, Aris ; Karacsonyi, Judit ; Danek, Barbara A. ; Resendes, Erica ; Martinez Parachini, Jose R. ; Kalsaria, Pratik ; Roesle, Michele ; Rangan, Bavana V. ; Sorajja, Paul ; Jneid, Hani ; Banerjee, Subhash ; Brilakis, Emmanouil S. / Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology guidelines for the management of patients with non-ST-segment elevation acute coronary syndromes. In: Coronary Artery Disease. 2017.
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abstract = "INTRODUCTION: The American College of Cardiology (ACC), the American Heart Association (AHA), and the European Society of Cardiology (ESC) have been developing guidelines to assist clinicians in making evidence-based decisions. MATERIALS AND METHODS: The current ACC/AHA and ESC guidelines for non-ST-segment elevation acute coronary syndromes (NSTE-ACS) that were updated in 2014 and 2015, respectively, were compared to assess the number of recommendations on the basis of class of recommendation and level of evidence (LOE), the sources cited, and the content. RESULTS: The total number of recommendations in the ACC/AHA and ESC guidelines was 182 and 147, respectively. The recommendation class distribution of the ACC/AHA guidelines was 61.0{\%} class I (compared with 61.9{\%} in the ESC guidelines, P=0.865), 29.7{\%} class II (compared with 32.0{\%} in the ESC guidelines, P=0.653), and 9.3{\%} class III (compared with 6.1{\%} in the ESC guidelines, P=0.282). The LOE distribution among ACC/AHA guidelines was 15.9{\%} LOE A (compared with 27.9{\%} in the ESC guidelines, P=0.008), 50.0{\%} LOE B (compared with 33.3{\%} in the ESC guidelines, P=0.002), and 34.1{\%} LOE C (compared with 38.8{\%} in the ESC guidelines, P=0.377). The ACC/AHA guidelines cited 827 publications and the ESC guidelines cited 551 publications, 124 of which were shared by both sets of guidelines. The guidelines’ approaches to NSTE-ACS were consistent, with minor differences in diagnostic and medical therapy recommendations. CONCLUSION: Overall, the ACC/AHA and ESC guidelines contain a comparable number of recommendations and provide similar guidance for the management of patients with NSTE-ACS.",
author = "Alame, {Aya J.} and Aris Karatasakis and Judit Karacsonyi and Danek, {Barbara A.} and Erica Resendes and {Martinez Parachini}, {Jose R.} and Pratik Kalsaria and Michele Roesle and Rangan, {Bavana V.} and Paul Sorajja and Hani Jneid and Subhash Banerjee and Brilakis, {Emmanouil S.}",
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T1 - Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology guidelines for the management of patients with non-ST-segment elevation acute coronary syndromes

AU - Alame, Aya J.

AU - Karatasakis, Aris

AU - Karacsonyi, Judit

AU - Danek, Barbara A.

AU - Resendes, Erica

AU - Martinez Parachini, Jose R.

AU - Kalsaria, Pratik

AU - Roesle, Michele

AU - Rangan, Bavana V.

AU - Sorajja, Paul

AU - Jneid, Hani

AU - Banerjee, Subhash

AU - Brilakis, Emmanouil S.

PY - 2017/3/16

Y1 - 2017/3/16

N2 - INTRODUCTION: The American College of Cardiology (ACC), the American Heart Association (AHA), and the European Society of Cardiology (ESC) have been developing guidelines to assist clinicians in making evidence-based decisions. MATERIALS AND METHODS: The current ACC/AHA and ESC guidelines for non-ST-segment elevation acute coronary syndromes (NSTE-ACS) that were updated in 2014 and 2015, respectively, were compared to assess the number of recommendations on the basis of class of recommendation and level of evidence (LOE), the sources cited, and the content. RESULTS: The total number of recommendations in the ACC/AHA and ESC guidelines was 182 and 147, respectively. The recommendation class distribution of the ACC/AHA guidelines was 61.0% class I (compared with 61.9% in the ESC guidelines, P=0.865), 29.7% class II (compared with 32.0% in the ESC guidelines, P=0.653), and 9.3% class III (compared with 6.1% in the ESC guidelines, P=0.282). The LOE distribution among ACC/AHA guidelines was 15.9% LOE A (compared with 27.9% in the ESC guidelines, P=0.008), 50.0% LOE B (compared with 33.3% in the ESC guidelines, P=0.002), and 34.1% LOE C (compared with 38.8% in the ESC guidelines, P=0.377). The ACC/AHA guidelines cited 827 publications and the ESC guidelines cited 551 publications, 124 of which were shared by both sets of guidelines. The guidelines’ approaches to NSTE-ACS were consistent, with minor differences in diagnostic and medical therapy recommendations. CONCLUSION: Overall, the ACC/AHA and ESC guidelines contain a comparable number of recommendations and provide similar guidance for the management of patients with NSTE-ACS.

AB - INTRODUCTION: The American College of Cardiology (ACC), the American Heart Association (AHA), and the European Society of Cardiology (ESC) have been developing guidelines to assist clinicians in making evidence-based decisions. MATERIALS AND METHODS: The current ACC/AHA and ESC guidelines for non-ST-segment elevation acute coronary syndromes (NSTE-ACS) that were updated in 2014 and 2015, respectively, were compared to assess the number of recommendations on the basis of class of recommendation and level of evidence (LOE), the sources cited, and the content. RESULTS: The total number of recommendations in the ACC/AHA and ESC guidelines was 182 and 147, respectively. The recommendation class distribution of the ACC/AHA guidelines was 61.0% class I (compared with 61.9% in the ESC guidelines, P=0.865), 29.7% class II (compared with 32.0% in the ESC guidelines, P=0.653), and 9.3% class III (compared with 6.1% in the ESC guidelines, P=0.282). The LOE distribution among ACC/AHA guidelines was 15.9% LOE A (compared with 27.9% in the ESC guidelines, P=0.008), 50.0% LOE B (compared with 33.3% in the ESC guidelines, P=0.002), and 34.1% LOE C (compared with 38.8% in the ESC guidelines, P=0.377). The ACC/AHA guidelines cited 827 publications and the ESC guidelines cited 551 publications, 124 of which were shared by both sets of guidelines. The guidelines’ approaches to NSTE-ACS were consistent, with minor differences in diagnostic and medical therapy recommendations. CONCLUSION: Overall, the ACC/AHA and ESC guidelines contain a comparable number of recommendations and provide similar guidance for the management of patients with NSTE-ACS.

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