TY - JOUR
T1 - Comparison of Transradial and Transfemoral Approaches in Women Undergoing Percutaneous Coronary Intervention in China
T2 - A Retrospective Observational Study
AU - Jin, Chen
AU - Xu, Yi
AU - Qiao, Shubin
AU - Tang, Xinran
AU - Wu, Yongjian
AU - Yan, Hongbing
AU - Dou, Kefei
AU - Xu, Bo
AU - Yang, Jingang
AU - Xian, Ying
AU - Yang, Yuejin
N1 - Publisher Copyright:
© SAGE Publications.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Despite increasing adoption of the transradial approach for percutaneous coronary intervention (PCI) in clinical practice, the role of transradial intervention (TRI) in women remains a significant debate. We identified 1392 women from a consecutive cohort of patients undergoing PCI in China in 2010 and compared the efficacy and hospital costs between TRI and transfemoral intervention. An inverse probability weighting (IPW) method was used to control for potential bias. After IPW adjustment, patients receiving TRI were less likely to experience post-PCI bleeding (adjusted odds ratio [OR]: 0.46, 95% confidence interval [CI]: 0.30-0.71) and major adverse cardiac events (adjusted OR 0.35, 95% CI 0.19-0.63) and more likely to have shorter length of stay in hospital (1.2 days difference, 95% CI: 0.6-1.7). Moreover, TRI was associated with a cost saving of ¥ (Yuan Renminbi) 7474 (approximately US$1150, 95% CI: ¥2993-¥11 624). More than 70% of this saving was driven by lower PCI-related costs. In conclusion, the use of TRI in women was associated with more favorable outcomes and lower hospital costs.
AB - Despite increasing adoption of the transradial approach for percutaneous coronary intervention (PCI) in clinical practice, the role of transradial intervention (TRI) in women remains a significant debate. We identified 1392 women from a consecutive cohort of patients undergoing PCI in China in 2010 and compared the efficacy and hospital costs between TRI and transfemoral intervention. An inverse probability weighting (IPW) method was used to control for potential bias. After IPW adjustment, patients receiving TRI were less likely to experience post-PCI bleeding (adjusted odds ratio [OR]: 0.46, 95% confidence interval [CI]: 0.30-0.71) and major adverse cardiac events (adjusted OR 0.35, 95% CI 0.19-0.63) and more likely to have shorter length of stay in hospital (1.2 days difference, 95% CI: 0.6-1.7). Moreover, TRI was associated with a cost saving of ¥ (Yuan Renminbi) 7474 (approximately US$1150, 95% CI: ¥2993-¥11 624). More than 70% of this saving was driven by lower PCI-related costs. In conclusion, the use of TRI in women was associated with more favorable outcomes and lower hospital costs.
KW - coronary artery disease
KW - cost-benefit analysis
KW - percutaneous coronary intervention
KW - transfemoral intervention
KW - transradial intervention
KW - women
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U2 - 10.1177/0003319716685670
DO - 10.1177/0003319716685670
M3 - Article
C2 - 28056519
AN - SCOPUS:85028877487
SN - 0003-3197
VL - 68
SP - 799
EP - 806
JO - Angiology
JF - Angiology
IS - 9
ER -