Complement system

Kim B. Yancey, Zelmira Lazarova

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Complement plays an important role in inflammation, opsonization of foreign materials, facilitation of phagocytosis by leukocytes, and direct cytotoxic reactions. The complement system is divided into three segments: initiation mechanisms, the amplification pathway, and the membrane attack complex. The initiation mechanisms are the classic, alternative, and lectin pathways. The complement system displays continuous, low-grade activation.

Original languageEnglish (US)
Title of host publicationClinical and Basic Immunodermatology
PublisherSpringer London
Pages105-118
Number of pages14
ISBN (Print)9781848001640
DOIs
StatePublished - Dec 1 2008

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Yancey, K. B., & Lazarova, Z. (2008). Complement system. In Clinical and Basic Immunodermatology (pp. 105-118). Springer London. https://doi.org/10.1007/978-1-84800-165-7_7