Complementation of mutation in Acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells

Medicine & Life Sciences

• Sterol O-Acyltransferase 100%
• Sterols 77%
• 25-hydroxycholesterol 68%
• Cricetinae 67%
• Mutation 37%
• Alleles 16%
• Sterol Regulatory Element Binding Protein 1 15%
• Cholesterol Esters 13%
• LDL Receptors 12%
• Enzymes 12%
• Cricetulus 11%
• Codon 10%
• Point Mutation 10%
• LDL Cholesterol 9%
• Ovary 9%
• Transfection 9%
• Complementary DNA 8%
• Messenger RNA 6%

Chemical Compounds

• Acyl-CoA 85%
• Sterol 72%
• 25-Hydroxycholesterol 62%
• Cholesterol 59%
• Mutation 56%
• Cleavage 19%
• Cholesteryl Ester 12%
• Complementary DNA 9%
• Protein 3%