Composite tissue transplantation: More science and patience needed

Research output: Contribution to journalReview article

42 Scopus citations

Abstract

Composite tissue transplantation offers promising solution for many reconstructive problems,including but not limited to extremity amputation. Although the current hand transplant recipients have demonstrated survival of allografs on high-dose immunosuppression,the risk benefit balance remains precarious for transplants aimed toward improving the quality of the recipient's life. Succesful adaption of tolerance induction modalities would reduce or eliminate the need for chronic immunosuppression.We thus advocate further scientific studies before the broad application of composite tissue transplants.

Original languageEnglish (US)
Pages (from-to)1066-1070
Number of pages5
JournalPlastic and reconstructive surgery
Volume107
Issue number4
StatePublished - Apr 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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