Concise synthesis of L-α-phosphatidyl-D-myo-inositol 3,4-bisphosphate, an intracellular second messenger

K. Kishta Reddy, Jose Rizo-Rey, J R Falck

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A highly efficient, asymmetric total synthesis of the title phospholipid as well as short chain diester and cross-linkable diether analogs was achieved in six steps from the readily available cyclitol 1.

Original languageEnglish (US)
Pages (from-to)4729-4730
Number of pages2
JournalTetrahedron Letters
Volume38
Issue number27
DOIs
StatePublished - Jul 7 1997

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Cyclitols
Second Messenger Systems
Phospholipids
inositol 3,4-bisphosphate

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Concise synthesis of L-α-phosphatidyl-D-myo-inositol 3,4-bisphosphate, an intracellular second messenger. / Reddy, K. Kishta; Rizo-Rey, Jose; Falck, J R.

In: Tetrahedron Letters, Vol. 38, No. 27, 07.07.1997, p. 4729-4730.

Research output: Contribution to journalArticle

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