Concomitant use of clopidogrel and proton-pump inhibitor: A reality check

Subhash Banerjee; Ahmad Zankar; Rick Weideman; Bertis Little; Emmanouil S. Brilakis

doi:10.2217/ica.10.12

Concomitant use of clopidogrel and proton-pump inhibitor: A reality check

Subhash Banerjee, Ahmad Zankar, Rick Weideman, Bertis Little, Emmanouil S. Brilakis

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

There are emerging reports supporting the fact that proton-pump inhibitors competitively inhibit the metabolism of clopidogrel to its active metabolite and diminish its clinical efficacy, especially in patients on long-term dual antiplatelet therapy. In this article, we examine the current evidence and provide interpretation of the results along with practical recommendations for healthcare providers.

Original language	English (US)
Pages (from-to)	121-125
Number of pages	5
Journal	Interventional Cardiology
Volume	2
Issue number	2
DOIs	https://doi.org/10.2217/ica.10.12
State	Published - Apr 2010

Keywords

cardiovascular outcome
clopidogrel
proton-pump inhibitor

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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Concomitant use of clopidogrel and proton-pump inhibitor: A reality check

Abstract

Keywords

ASJC Scopus subject areas

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