Concurrent measurement of skeletal muscle blood flow during exercise with diffuse correlation spectroscopy and Doppler ultrasound

Chandan Ganesh Bangalore-Yogananda; Ryan Rosenberry; Sagar Soni; Hanli Liu; Michael D. Nelson; Fenghua Tian

doi:10.1364/BOE.9.000131

Concurrent measurement of skeletal muscle blood flow during exercise with diffuse correlation spectroscopy and Doppler ultrasound

Chandan Ganesh Bangalore-Yogananda, Ryan Rosenberry, Sagar Soni, Hanli Liu, Michael D. Nelson, Fenghua Tian

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a postexercise recovery. The results from DCS and Doppler ultrasound were highly correlated (R = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.

Original language	English (US)
Article number	#306844
Pages (from-to)	131-141
Number of pages	11
Journal	Biomedical Optics Express
Volume	9
Issue number	1
DOIs	https://doi.org/10.1364/BOE.9.000131
State	Published - Jan 1 2018
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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abstract = "Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a postexercise recovery. The results from DCS and Doppler ultrasound were highly correlated (R = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.",

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AU - Tian, Fenghua

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Concurrent measurement of skeletal muscle blood flow during exercise with diffuse correlation spectroscopy and Doppler ultrasound

Abstract

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