Concurrent variations of cerebral blood flow and arterial blood pressure in simulated sleep apnea

Raichel Alex, Gauri Bhave, Mohammad A. Al-Abed, Aditya Bashaboyina, Swathi Iyer, Donald E. Watenpaugh, Rong Zhang, Khosrow Behbehani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Obstructive Sleep Apnea (OSA) is one of the most common sleep disordered breathing which affects about 15 % of US adult population. OSA is considered to be an important risk factor for the development of cardiac dysfunction and stroke. In this paper, we present the initial results of our investigation of the relationship between arterial blood pressure and cerebral blood flow velocity in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 294.89 yrs age and body mass index of 24.074.84 kg/m 2 participated in the study. Our findings indicate that cerebral blood flow velocity variations has a relatively high correlation to changes in blood pressure during simulated apnea (r0.74 0.06), suggesting that cerebral autoregulation may not compensate for the pressure changes during apnea.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages3209-3212
Number of pages4
DOIs
StatePublished - 2011
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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