TY - JOUR
T1 - Concurrent variations of cerebral blood flow and arterial blood pressure in simulated sleep apnea.
AU - Alex, Raichel
AU - Bhave, Gauri
AU - Al-Abed, Mohammad A.
AU - Bashaboyina, Aditya
AU - Iyer, Swathi
AU - Watenpaugh, Donald E.
AU - Zhang, Rong
AU - Behbehani, Khosrow
PY - 2011
Y1 - 2011
N2 - Obstructive Sleep Apnea (OSA) is one of the most common sleep disordered breathing which affects about 15 % of US adult population. OSA is considered to be an important risk factor for the development of cardiac dysfunction and stroke. In this paper, we present the initial results of our investigation of the relationship between arterial blood pressure and cerebral blood flow velocity in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29 ± 4.89 yrs age and body mass index of 24.07 ± 4.84 kg/m(2) participated in the study. Our findings indicate that cerebral blood flow velocity variations has a relatively high correlation to changes in blood pressure during simulated apnea (r = 0.74 ± 0.06), suggesting that cerebral autoregulation may not compensate for the pressure changes during apnea.
AB - Obstructive Sleep Apnea (OSA) is one of the most common sleep disordered breathing which affects about 15 % of US adult population. OSA is considered to be an important risk factor for the development of cardiac dysfunction and stroke. In this paper, we present the initial results of our investigation of the relationship between arterial blood pressure and cerebral blood flow velocity in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29 ± 4.89 yrs age and body mass index of 24.07 ± 4.84 kg/m(2) participated in the study. Our findings indicate that cerebral blood flow velocity variations has a relatively high correlation to changes in blood pressure during simulated apnea (r = 0.74 ± 0.06), suggesting that cerebral autoregulation may not compensate for the pressure changes during apnea.
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M3 - Article
C2 - 22255022
AN - SCOPUS:84862622189
SN - 1557-170X
VL - 2011
SP - 3209
EP - 3212
JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
ER -