Conjunctival resection treatment and ultrastructural histopathology of superior limbic keratoconjunctivitis

P. C. Donshik, H. B. Collin, C. S. Foster, Harrison D Cavanagh, S. A. Boruchoff

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Four patients with symptomatic superior limbic keratoconjunctivitis underwent resection of the superior bulbar conjunctiva. One of these patients also underwent a tarsal conjunctival resection in the other eye. Three of the patients had previously been treated by various regimens without resolution; the fourth had had no prior treatment. All four patients had immediate and continued relief of the ocular symptoms after the superior bulbar conjunctiva was excised. The patient who underwent tarsal conjunctival resection experienced only short-term relief. The authors studied the conjunctival tissue by light and transmission electron microscopy. Both techniques revealed abnormalities related to the bulbar conjunctival surface with keratinization of the epithelium, acanthosis, degeneration of the nuclei, and intracellular accumulation of glycogen. Inflammatory cells were minimally present. The tarsal conjunctiva appeared essentially normal.

Original languageEnglish (US)
Pages (from-to)101-110
Number of pages10
JournalUnknown Journal
Volume85
Issue number1
DOIs
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Ophthalmology

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