CONSIDERATIONS FOR SPATIAL AND TEMPORAL QUANTIZATION OF REGIONAL MYOCARDIAL PERFUSION DATA.

E. M. Stokeley, L. R. Nardizzi, R. W. Parkey, F. J. Bonte

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Inert gas isotopes are finding more commonplace use in the measurement of blood perfusion in the capillary beds of patients who have experienced the symptoms of a myocardial infarction. This study analyzes the effects on the calculated perfusion rate of various techniques for collecting and displaying clearance curves following a bolus injection of the inert gas isotope into the left coronary artery of the dog. The study is motivated by the need to maximize the sampling period (data collection time for one point on the clearance curve), minimize the observation time (total length of the clearance curve) and to maximize the spatial sampling interval (size of the regional area selected for investigation). The resulting procedure minimizes patient exposure to radiation, since smaller isotope dosage is required to produce statistically significant clearance curves. In addition, bulk storage costs are minimized by eliminating the storage of unnecessary data.

Original languageEnglish (US)
Title of host publicationUnknown Host Publication Title
Place of PublicationCalif
PublisherSan Diego Biomed Symp (v 12)
Pages237-240
Number of pages4
StatePublished - 1973
EventSan Diego Biomed Symp, Proc - San Diego, CA, USA
Duration: Jan 31 1973Feb 2 1973

Other

OtherSan Diego Biomed Symp, Proc
CitySan Diego, CA, USA
Period1/31/732/2/73

ASJC Scopus subject areas

  • General Engineering

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