Considering the influence of stimulation parameters on the effect of conventional and high-definition transcranial direct current stimulation

Wing Ting To, John Hart, Dirk De Ridder, Sven Vanneste

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Recently, techniques to non-invasively modulate specific brain areas gained popularity in the form of transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation. These non-invasive techniques have already shown promising outcomes in various studies with healthy subjects as well as patient populations. Despite widespread dissemination of tDCS, there remain significant unknowns about the influence of a diverse number of tDCS parameters (e.g. polarity, size, position of electrodes & duration of stimulation) in inducing neurophysiological and behavioral effects. This article explores both techniques starting with the history of tDCS, to the differences between conventional tDCS and high-definition transcranial direct current stimulation, the underlying physiological mechanism, the (in)direct effects, the applications of tDCS with varying parameters, the efficacy, the safety issues and the opportunities for future research.

Original languageEnglish (US)
Pages (from-to)391-404
Number of pages14
JournalExpert Review of Medical Devices
Volume13
Issue number4
DOIs
StatePublished - Apr 2 2016

Keywords

  • HD-tDCS
  • neuromodulation
  • Non-invasive
  • stimulation parameters
  • transcranial direct current stimulation

ASJC Scopus subject areas

  • Surgery
  • Biomedical Engineering

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