Constructing a lattice of Infectious Disease Ontologies from a Staphylococcus aureus isolate repository

Albert Goldfain, Barry Smith, Lindsay G. Cowell

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A repository of clinically associated Staphylococcus aureus (Sa) isolates is used to semi-automatically generate a set of application ontologies for specific subfamilies of Sa-related disease. Each such application ontology is compatible with the Infectious Disease Ontology (IDO) and uses resources from the Open Biomedical Ontology (OBO) Foundry. The set of application ontologies forms a lattice structure beneath the IDO-Core and IDO-extension reference ontologies. We show howthis lattice can be used to define a strategy for the construction of a new taxonomy of infectious disease incorporating genetic, molecular, and clinical data. We also outline how faceted browsing and query of annotated data is supported using a lattice application ontology.

Original languageEnglish (US)
Title of host publicationCEUR Workshop Proceedings
StatePublished - 2012
Event3rd International Conference on Biomedical Ontology 2012, ICBO 2012 - Graz, Austria
Duration: Jul 21 2012Jul 25 2012


Other3rd International Conference on Biomedical Ontology 2012, ICBO 2012


ASJC Scopus subject areas

  • Computer Science(all)

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