Contemporary extracorporeal membrane oxygenation therapy in adults: Fundamental principles and systematic review of the evidence

John J. Squiers, Brian Lima, J. Michael DiMaio

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Extracorporeal membrane oxygenation (ECMO) provides days to weeks of support for patients with respiratory, cardiac, or combined cardiopulmonary failure. Since ECMO was first reported in 1974, nearly 70,000 runs of ECMO have been implemented, and the use of ECMO in adults increased by more than 400% from 2006 to 2011 in the United States. A variety of factors, including the 2009 influenza A epidemic, results from recent clinical trials, and improvements in ECMO technology, have motivated this increased use in adults. Because ECMO is increasingly becoming available to a diverse population of critically ill patients, we provide an overview of its fundamental principles and a systematic review of the evidence basis of this treatment modality for a variety of indications in adults.

Original languageEnglish (US)
JournalJournal of Thoracic and Cardiovascular Surgery
DOIs
StateAccepted/In press - 2016

Keywords

  • Adult respiratory distress syndrome
  • Cardiogenic shock
  • Extracorporeal cardiopulmonary resuscitation
  • Extracorporeal membrane oxygenation
  • Systematic review

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

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