Contemporary Management of Nonfunctioning Pancreatic Neuroendocrine Tumors

Rebecca M. Minter, Diane M. Simeone

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Background: This article reviews the current literature and recommendations pertaining to the management of nonfunctioning pancreatic neuroendocrine tumors. Discussion: In recent years the detection of nonfunctioning pancreatic neuroendocrine tumors has increased coincident with the increased use of cross-sectional imaging and is now thought to represent 2-10% of all pancreatic tumors. Improved understanding of the biology and behavior of these heterogeneous tumors is needed to guide therapy. The present review discusses diagnostics, therapeutics including emerging molecular analytics, and surveillance recommendations.

Original languageEnglish (US)
Pages (from-to)435-446
Number of pages12
JournalJournal of Gastrointestinal Surgery
Volume16
Issue number2
DOIs
StatePublished - Feb 1 2012

Keywords

  • NF-PNET
  • Neuroendocrine tumor
  • Nonfunctioning
  • Pancreas
  • Pancreatic

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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