TY - JOUR
T1 - Contemporary Management of Severely Calcified Coronary Lesions
AU - Angsubhakorn, Natthapon
AU - Kang, Nicolas
AU - Fearon, Colleen
AU - Techorueangwiwat, Chol
AU - Swamy, Pooja
AU - Brilakis, Emmanouil S.
AU - Bharadwaj, Aditya S.
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2022/10
Y1 - 2022/10
N2 - Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality’s relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.
AB - Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality’s relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.
KW - coronary artery calcification
KW - intravascular imaging
KW - percutaneous coronary intervention
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U2 - 10.3390/jpm12101638
DO - 10.3390/jpm12101638
M3 - Review article
C2 - 36294777
AN - SCOPUS:85140629626
SN - 2075-4426
VL - 12
JO - Journal of Personalized Medicine
JF - Journal of Personalized Medicine
IS - 10
M1 - 1638
ER -