Continuous donor perfusion for heart preservation

Richard Kirk, Anne I. Dipchand

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

One of the keys to successful cardiac transplantation is preservation of the heart during explantation, transport and implantation. To date the most commonly used method has been cold static storage and this currently remains the only method available for pediatric recipients. However, there has long been interest in continuous perfusion of the donor organ during the ex vivo period to mitigate the effects of ischemia and this is now becoming a clinical reality for adult recipients with good short and early midterm results. Data to date however suggests that the greatest benefit lies in preserving marginal organs, especially those following circulatory death, or when a prolonged ischemic time can be predicted.

Original languageEnglish (US)
Pages (from-to)15-18
Number of pages4
JournalProgress in Pediatric Cardiology
Volume46
DOIs
StatePublished - Sep 1 2017

Fingerprint

Perfusion
Tissue Donors
Heart Transplantation
Ischemia
Pediatrics

Keywords

  • Continuous
  • Donor
  • Heart
  • Perfusion
  • Preservation
  • Transplant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

Cite this

Continuous donor perfusion for heart preservation. / Kirk, Richard; Dipchand, Anne I.

In: Progress in Pediatric Cardiology, Vol. 46, 01.09.2017, p. 15-18.

Research output: Contribution to journalReview article

Kirk, Richard ; Dipchand, Anne I. / Continuous donor perfusion for heart preservation. In: Progress in Pediatric Cardiology. 2017 ; Vol. 46. pp. 15-18.
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