Continuous transversus abdominis plane block catheter analgesia for postoperative pain control in renal transplant

Ehab Farag, Maged N. Guirguis, Mada Helou, Jarrod E. Dalton, Fallon Ngo, Michael Ghobrial, Jerome O’Hara, John Seif, Venkatesh Krishnamurthi, David Goldfarb

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14 Scopus citations

Abstract

Purpose: Continuous transversus abdominis plane (TAP) block using a catheter has proven its usefulness in reducing opioid requirements and pain scores after lower abdominal surgery. However, there are no reports of its successful use after renal transplant. We tested the hypothesis that continuous TAP block would retrospectively reduce opioid requirement, nausea score and hospital stay after renal transplant surgery.

Methods: In a retrospective study, we reviewed the data from 63 adult renal transplant recipients—31 with patient-controlled TAP analgesia with standing orders for intravenous as well as oral opioids as needed and 32 with intravenous patient-controlled analgesia. The TAP catheter was inserted preoperatively using an ultrasound-guided technique. Infusion of ropivacaine 0.2 % at 8 ml basal, 12 ml bolus and a lockout interval of 60 min were maintained for 48 h postoperatively. The primary outcome was total morphine-equivalent dose during the 48-h postoperative period. Secondary outcomes were pain and nausea scores for the 48-h postoperative period.

Results: The mean 48-h postoperative morphine-equivalent doses [95 % confidence interval] for patient-controlled intravenous analgesia and TAP catheter were 197 [111, 349] and 50 [28, 90], respectively, which were significantly different (P = 0.002). The mean 48-h average verbal response pain scores were 2.94 [2.39, 3.50] and 2.49 [1.93, 3.06], respectively, which were not significantly different (P = 0.26). The mean nausea scores were 0.66 [0.46, 0.87] and 0.60 [0.40, 0.81], respectively, which were not significantly different (P = 0.69). There was no difference regarding hospital stay.

Conclusion: The use of continuous TAP analgesia for postoperative analgesia after renal transplant was effective in reducing the morphine-equivalent requirements.

Original languageEnglish (US)
Pages (from-to)4-8
Number of pages5
JournalJournal of Anesthesia
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • Abdominal surgery
  • Kidney transplantation
  • Local anesthetic − ropivacaine
  • Nausea
  • Opioid analgesics − morphine
  • TAP catheter

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Farag, E., Guirguis, M. N., Helou, M., Dalton, J. E., Ngo, F., Ghobrial, M., O’Hara, J., Seif, J., Krishnamurthi, V., & Goldfarb, D. (2014). Continuous transversus abdominis plane block catheter analgesia for postoperative pain control in renal transplant. Journal of Anesthesia, 29(1), 4-8. https://doi.org/10.1007/s00540-014-1855-1