Acid-base homeostasis constitutes one of the most fundamental biologic processes vital to survival of all life-forms. Derangements acid-base balance can result from a variety of causes and can exert multiple effects on many organs. Metabolic acidosis is a state of excess accumulation of acid in the body due to excess production, reduced excretion, or a combination of both. In this chapter, we summarize some basic acid-base chemistry and biology for the clinician, highlights how to utilize simple laboratory findings to approach metabolic acidosis, and finally discuss the evidence that supports the various treatment protocols and controversies in metabolic acidosis.
|Original language||English (US)|
|Title of host publication||Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance|
|Number of pages||40|
|ISBN (Print)||1461437695, 9781461437697|
|State||Published - Nov 1 2013|
ASJC Scopus subject areas