Corneal endothelial transplantation

J. P. McCulley, D. M. Maurice, B. D. Schwartz

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Patients with visually significant corneal edema, secondary to endothelial dysfunction, before the development of scarring or vascularization, need only have the corneal endothelium replaced to restore corneal clarity. This fact, plus the lack of consistently available donor material, prompted the authors to evaluate tissue cultured corneal endothelium (TCCE) as a donor source. They have shown that TCCE, when transplanted, can regain normal morphology and physiologic function. To accomplish practical use of autologous stroma, a transparent gelatin membrane which can serve as substrate for endothelial growth in tissue culture, has been developed. This cellular membrane has been transplanted successfully in rabbits with good functional results. It is hoped that ultimately this technique can be developed for routine use in man.

Original languageEnglish (US)
Pages (from-to)194-201
Number of pages8
JournalOphthalmology
Volume87
Issue number3
StatePublished - 1980

Fingerprint

Corneal Endothelium
Corneal Transplantation
Tissue Donors
Corneal Edema
Membranes
Gelatin
Cicatrix
Rabbits
Growth

ASJC Scopus subject areas

  • Ophthalmology

Cite this

McCulley, J. P., Maurice, D. M., & Schwartz, B. D. (1980). Corneal endothelial transplantation. Ophthalmology, 87(3), 194-201.

Corneal endothelial transplantation. / McCulley, J. P.; Maurice, D. M.; Schwartz, B. D.

In: Ophthalmology, Vol. 87, No. 3, 1980, p. 194-201.

Research output: Contribution to journalArticle

McCulley, JP, Maurice, DM & Schwartz, BD 1980, 'Corneal endothelial transplantation', Ophthalmology, vol. 87, no. 3, pp. 194-201.
McCulley JP, Maurice DM, Schwartz BD. Corneal endothelial transplantation. Ophthalmology. 1980;87(3):194-201.
McCulley, J. P. ; Maurice, D. M. ; Schwartz, B. D. / Corneal endothelial transplantation. In: Ophthalmology. 1980 ; Vol. 87, No. 3. pp. 194-201.
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