“Corneal Nerves, CD11c+ Dendritic Cells and Their Impact on Ocular Immune Privilege”

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2 Scopus citations

Abstract

The eye and the brain have limited capacities for regeneration and as such, immune-mediated inflammation can produce devastating consequences in the form of neurodegenerative diseases of the central nervous system or blindness as a result of ocular inflammatory diseases such as uveitis. Accordingly, both the eye and the brain are designed to limit immune responses and inflammation – a condition known as “immune privilege”. Immune privilege is sustained by physiological, anatomical, and regulatory processes that conspire to restrict both adaptive and innate immune responses.

Original languageEnglish (US)
Article number701935
JournalFrontiers in immunology
Volume12
DOIs
StatePublished - Jun 18 2021

Keywords

  • contrasuppressor cells
  • cornea
  • dendritic cells
  • immune privilege
  • nerves

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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