Coronary angiographic scoring systems: An evaluation of their equivalence and validity

Ian J. Neeland, Riyaz S. Patel, Parham Eshtehardi, Saurabh Dhawan, Michael C. McDaniel, S. Tanveer Rab, Viola Vaccarino, A. Maziar Zafari, Habib Samady, Arshed A. Quyyumi

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Background: Multiple scoring systems have been devised to quantify angiographic coronary artery disease (CAD) burden, but it is unclear how these scores relate to each other and which scores are most accurate. The aim of this study was to compare coronary angiographic scoring systems (1) with each other and (2) with intravascular ultrasound (IVUS)-derived plaque burden in a population undergoing angiographic evaluation for CAD. Methods: Coronary angiographic data from 3600 patients were scored using 10 commonly used angiographic scoring systems and interscore correlations were calculated. In a subset of 50 patients, plaque burden and plaque area in the left anterior descending coronary artery were quantified using IVUS and correlated with angiographic scores. Results: All angiographic scores correlated with each other (range for Spearman coefficient [ρ] 0.79-0.98, P <.0001); the 2 most widely used scores, Gensini and CASS-70, had a ρ = 0.90 (P <.0001). All scores correlated significantly with average plaque burden and plaque area by IVUS (range ρ 0.56-0.78, P <.0001 and 0.43-0.62, P <.01, respectively). The CASS-50 score had the strongest correlation (ρ 0.78 and 0.62, P <.0001) and the Duke Jeopardy score the weakest correlation (ρ 0.56 and 0.43, P <.01) with plaque burden and area, respectively. Conclusions: Angiographic scoring systems are strongly correlated with each other and with atherosclerotic plaque burden. Scoring systems therefore appear to be a valid estimate of CAD plaque burden.

Original languageEnglish (US)
JournalAmerican Heart Journal
Volume164
Issue number4
DOIs
StatePublished - Oct 1 2012

Fingerprint

Coronary Artery Disease
Atherosclerotic Plaques
Coronary Vessels
Population
6-chloropenicillanic acid S-sulfoxide

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Neeland, I. J., Patel, R. S., Eshtehardi, P., Dhawan, S., McDaniel, M. C., Rab, S. T., ... Quyyumi, A. A. (2012). Coronary angiographic scoring systems: An evaluation of their equivalence and validity. American Heart Journal, 164(4). https://doi.org/10.1016/j.ahj.2012.07.007

Coronary angiographic scoring systems : An evaluation of their equivalence and validity. / Neeland, Ian J.; Patel, Riyaz S.; Eshtehardi, Parham; Dhawan, Saurabh; McDaniel, Michael C.; Rab, S. Tanveer; Vaccarino, Viola; Zafari, A. Maziar; Samady, Habib; Quyyumi, Arshed A.

In: American Heart Journal, Vol. 164, No. 4, 01.10.2012.

Research output: Contribution to journalArticle

Neeland, IJ, Patel, RS, Eshtehardi, P, Dhawan, S, McDaniel, MC, Rab, ST, Vaccarino, V, Zafari, AM, Samady, H & Quyyumi, AA 2012, 'Coronary angiographic scoring systems: An evaluation of their equivalence and validity', American Heart Journal, vol. 164, no. 4. https://doi.org/10.1016/j.ahj.2012.07.007
Neeland, Ian J. ; Patel, Riyaz S. ; Eshtehardi, Parham ; Dhawan, Saurabh ; McDaniel, Michael C. ; Rab, S. Tanveer ; Vaccarino, Viola ; Zafari, A. Maziar ; Samady, Habib ; Quyyumi, Arshed A. / Coronary angiographic scoring systems : An evaluation of their equivalence and validity. In: American Heart Journal. 2012 ; Vol. 164, No. 4.
@article{ad7acb7bd46b4fc99b79451fe93933f8,
title = "Coronary angiographic scoring systems: An evaluation of their equivalence and validity",
abstract = "Background: Multiple scoring systems have been devised to quantify angiographic coronary artery disease (CAD) burden, but it is unclear how these scores relate to each other and which scores are most accurate. The aim of this study was to compare coronary angiographic scoring systems (1) with each other and (2) with intravascular ultrasound (IVUS)-derived plaque burden in a population undergoing angiographic evaluation for CAD. Methods: Coronary angiographic data from 3600 patients were scored using 10 commonly used angiographic scoring systems and interscore correlations were calculated. In a subset of 50 patients, plaque burden and plaque area in the left anterior descending coronary artery were quantified using IVUS and correlated with angiographic scores. Results: All angiographic scores correlated with each other (range for Spearman coefficient [ρ] 0.79-0.98, P <.0001); the 2 most widely used scores, Gensini and CASS-70, had a ρ = 0.90 (P <.0001). All scores correlated significantly with average plaque burden and plaque area by IVUS (range ρ 0.56-0.78, P <.0001 and 0.43-0.62, P <.01, respectively). The CASS-50 score had the strongest correlation (ρ 0.78 and 0.62, P <.0001) and the Duke Jeopardy score the weakest correlation (ρ 0.56 and 0.43, P <.01) with plaque burden and area, respectively. Conclusions: Angiographic scoring systems are strongly correlated with each other and with atherosclerotic plaque burden. Scoring systems therefore appear to be a valid estimate of CAD plaque burden.",
author = "Neeland, {Ian J.} and Patel, {Riyaz S.} and Parham Eshtehardi and Saurabh Dhawan and McDaniel, {Michael C.} and Rab, {S. Tanveer} and Viola Vaccarino and Zafari, {A. Maziar} and Habib Samady and Quyyumi, {Arshed A.}",
year = "2012",
month = "10",
day = "1",
doi = "10.1016/j.ahj.2012.07.007",
language = "English (US)",
volume = "164",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "4",

}

TY - JOUR

T1 - Coronary angiographic scoring systems

T2 - An evaluation of their equivalence and validity

AU - Neeland, Ian J.

AU - Patel, Riyaz S.

AU - Eshtehardi, Parham

AU - Dhawan, Saurabh

AU - McDaniel, Michael C.

AU - Rab, S. Tanveer

AU - Vaccarino, Viola

AU - Zafari, A. Maziar

AU - Samady, Habib

AU - Quyyumi, Arshed A.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - Background: Multiple scoring systems have been devised to quantify angiographic coronary artery disease (CAD) burden, but it is unclear how these scores relate to each other and which scores are most accurate. The aim of this study was to compare coronary angiographic scoring systems (1) with each other and (2) with intravascular ultrasound (IVUS)-derived plaque burden in a population undergoing angiographic evaluation for CAD. Methods: Coronary angiographic data from 3600 patients were scored using 10 commonly used angiographic scoring systems and interscore correlations were calculated. In a subset of 50 patients, plaque burden and plaque area in the left anterior descending coronary artery were quantified using IVUS and correlated with angiographic scores. Results: All angiographic scores correlated with each other (range for Spearman coefficient [ρ] 0.79-0.98, P <.0001); the 2 most widely used scores, Gensini and CASS-70, had a ρ = 0.90 (P <.0001). All scores correlated significantly with average plaque burden and plaque area by IVUS (range ρ 0.56-0.78, P <.0001 and 0.43-0.62, P <.01, respectively). The CASS-50 score had the strongest correlation (ρ 0.78 and 0.62, P <.0001) and the Duke Jeopardy score the weakest correlation (ρ 0.56 and 0.43, P <.01) with plaque burden and area, respectively. Conclusions: Angiographic scoring systems are strongly correlated with each other and with atherosclerotic plaque burden. Scoring systems therefore appear to be a valid estimate of CAD plaque burden.

AB - Background: Multiple scoring systems have been devised to quantify angiographic coronary artery disease (CAD) burden, but it is unclear how these scores relate to each other and which scores are most accurate. The aim of this study was to compare coronary angiographic scoring systems (1) with each other and (2) with intravascular ultrasound (IVUS)-derived plaque burden in a population undergoing angiographic evaluation for CAD. Methods: Coronary angiographic data from 3600 patients were scored using 10 commonly used angiographic scoring systems and interscore correlations were calculated. In a subset of 50 patients, plaque burden and plaque area in the left anterior descending coronary artery were quantified using IVUS and correlated with angiographic scores. Results: All angiographic scores correlated with each other (range for Spearman coefficient [ρ] 0.79-0.98, P <.0001); the 2 most widely used scores, Gensini and CASS-70, had a ρ = 0.90 (P <.0001). All scores correlated significantly with average plaque burden and plaque area by IVUS (range ρ 0.56-0.78, P <.0001 and 0.43-0.62, P <.01, respectively). The CASS-50 score had the strongest correlation (ρ 0.78 and 0.62, P <.0001) and the Duke Jeopardy score the weakest correlation (ρ 0.56 and 0.43, P <.01) with plaque burden and area, respectively. Conclusions: Angiographic scoring systems are strongly correlated with each other and with atherosclerotic plaque burden. Scoring systems therefore appear to be a valid estimate of CAD plaque burden.

UR - http://www.scopus.com/inward/record.url?scp=84867565966&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867565966&partnerID=8YFLogxK

U2 - 10.1016/j.ahj.2012.07.007

DO - 10.1016/j.ahj.2012.07.007

M3 - Article

C2 - 23067913

AN - SCOPUS:84867565966

VL - 164

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 4

ER -