Coronavirus HKU1 infection in the United States

Frank Esper, Carla Weibel, David Ferguson, Marie L. Landry, Jeffrey Kahn

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

In 2005, a new human coronavirus, HCoV-HKU1, was identified in Hong Kong. We screened respiratory specimens collected from December 16, 2001, to December 15, 2002, from children <5 years of age who tested negative for respiratory syncytial virus, parainfluenza viruses, influenza virus, and adenovirus for HCoV-HKU1 by reverse transcription-polymerase chain reaction. Overall, 1,048 respiratory specimens from 851 children were tested, and 9 HCoV-HKU1-positive children (1%) were identified, 2 of whom had 2 positive specimens. Children who had HCoV-HKU1 infection had evidence of either upper or lower respiratory tract infection or both. Two patients had disease beyond the respiratory tract. HCoV-HKU1 was identified from December 2001 to February 2002. Sequence analyses suggest that a single strain was circulating. HCoV-HKU1 is therefore likely circulating in the United States and is associated with upper and lower respiratory tract disease.

Original languageEnglish (US)
Pages (from-to)775-779
Number of pages5
JournalEmerging Infectious Diseases
Volume12
Issue number5
StatePublished - May 2006

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Coronavirus Infections
Respiratory Tract Diseases
Paramyxoviridae Infections
Coronavirus
Respiratory Syncytial Viruses
Hong Kong
Orthomyxoviridae
Adenoviridae
Respiratory Tract Infections
Reverse Transcription
Sequence Analysis
Viruses
Polymerase Chain Reaction
Infection

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Esper, F., Weibel, C., Ferguson, D., Landry, M. L., & Kahn, J. (2006). Coronavirus HKU1 infection in the United States. Emerging Infectious Diseases, 12(5), 775-779.

Coronavirus HKU1 infection in the United States. / Esper, Frank; Weibel, Carla; Ferguson, David; Landry, Marie L.; Kahn, Jeffrey.

In: Emerging Infectious Diseases, Vol. 12, No. 5, 05.2006, p. 775-779.

Research output: Contribution to journalArticle

Esper, F, Weibel, C, Ferguson, D, Landry, ML & Kahn, J 2006, 'Coronavirus HKU1 infection in the United States', Emerging Infectious Diseases, vol. 12, no. 5, pp. 775-779.
Esper F, Weibel C, Ferguson D, Landry ML, Kahn J. Coronavirus HKU1 infection in the United States. Emerging Infectious Diseases. 2006 May;12(5):775-779.
Esper, Frank ; Weibel, Carla ; Ferguson, David ; Landry, Marie L. ; Kahn, Jeffrey. / Coronavirus HKU1 infection in the United States. In: Emerging Infectious Diseases. 2006 ; Vol. 12, No. 5. pp. 775-779.
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