Corpus callosum damage and interhemispheric transfer of information following closed head injury in children

Debra A. Benavidez; Jack M. Fletcher; H. Julia Hannay; Sondra T. Bland; Susan E. Caudle; Dianne B. Mendelsohn; Joel Yeakley; Donald G. Brunder; Harriet Harward; James Song; Nancy A. Perachio; Derek Bruce; Randall S. Scheibel; Matthew A. Lilly; Katia Verger-Maestre; Harvey S. Levin

doi:10.1016/S0010-9452(08)70803-7

Corpus callosum damage and interhemispheric transfer of information following closed head injury in children

Debra A. Benavidez, Jack M. Fletcher, H. Julia Hannay, Sondra T. Bland, Susan E. Caudle, Dianne B. Mendelsohn, Joel Yeakley, Donald G. Brunder, Harriet Harward, James Song, Nancy A. Perachio, Derek Bruce, Randall S. Scheibel, Matthew A. Lilly, Katia Verger-Maestre, Harvey S. Levin

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

We evaluated the relationship of corpus callosum atrophy and/or lesions on magnetic resonance imaging (MRI) to functional hemispheric disconnection following closed head injury (CHI) in 51 pediatric patients, including mild CHI, moderate to severe CHI with extracallosal lesions, and moderate to severe CHI with callosal atrophy and/or lesions. Interhemispheric transfer of information was assessed using auditory, motor, tactile, and visual tests in patients and in 16 uninjured children. Total and regional callosal areas were measured from the midsagittal MRI slice by morphometry. The corpus callosum lesion group demonstrated a greater right ear advantage on verbal dichotic listening than all other groups. Areas of the posterior corpus callosum were negatively correlated with laterality indices of verbal dichotic listening performance and tachistoscopic identification of verbal material. The relationship of corpus callosum atrophy and/or lesions to asymmetry in dichotic listening is consistent with previous investigation of posttraumatic hemispheric disconnection effects in adults.

Original language	English (US)
Pages (from-to)	315-336
Number of pages	22
Journal	Cortex
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/S0010-9452(08)70803-7
State	Published - Jun 1999

Keywords

Children
Closed head injury
Corpus callosum
Dichotic listening

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Experimental and Cognitive Psychology
Cognitive Neuroscience

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Benavidez, D. A., Fletcher, J. M., Hannay, H. J., Bland, S. T., Caudle, S. E., Mendelsohn, D. B., Yeakley, J., Brunder, D. G., Harward, H., Song, J., Perachio, N. A., Bruce, D., Scheibel, R. S., Lilly, M. A., Verger-Maestre, K., & Levin, H. S. (1999). Corpus callosum damage and interhemispheric transfer of information following closed head injury in children. Cortex, 35(3), 315-336. https://doi.org/10.1016/S0010-9452(08)70803-7

Benavidez, DA, Fletcher, JM, Hannay, HJ, Bland, ST, Caudle, SE, Mendelsohn, DB, Yeakley, J, Brunder, DG, Harward, H, Song, J, Perachio, NA, Bruce, D, Scheibel, RS, Lilly, MA, Verger-Maestre, K & Levin, HS 1999, 'Corpus callosum damage and interhemispheric transfer of information following closed head injury in children', Cortex, vol. 35, no. 3, pp. 315-336. https://doi.org/10.1016/S0010-9452(08)70803-7

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abstract = "We evaluated the relationship of corpus callosum atrophy and/or lesions on magnetic resonance imaging (MRI) to functional hemispheric disconnection following closed head injury (CHI) in 51 pediatric patients, including mild CHI, moderate to severe CHI with extracallosal lesions, and moderate to severe CHI with callosal atrophy and/or lesions. Interhemispheric transfer of information was assessed using auditory, motor, tactile, and visual tests in patients and in 16 uninjured children. Total and regional callosal areas were measured from the midsagittal MRI slice by morphometry. The corpus callosum lesion group demonstrated a greater right ear advantage on verbal dichotic listening than all other groups. Areas of the posterior corpus callosum were negatively correlated with laterality indices of verbal dichotic listening performance and tachistoscopic identification of verbal material. The relationship of corpus callosum atrophy and/or lesions to asymmetry in dichotic listening is consistent with previous investigation of posttraumatic hemispheric disconnection effects in adults.",

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author = "Benavidez, {Debra A.} and Fletcher, {Jack M.} and Hannay, {H. Julia} and Bland, {Sondra T.} and Caudle, {Susan E.} and Mendelsohn, {Dianne B.} and Joel Yeakley and Brunder, {Donald G.} and Harriet Harward and James Song and Perachio, {Nancy A.} and Derek Bruce and Scheibel, {Randall S.} and Lilly, {Matthew A.} and Katia Verger-Maestre and Levin, {Harvey S.}",

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AU - Brunder, Donald G.

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AU - Perachio, Nancy A.

AU - Bruce, Derek

AU - Scheibel, Randall S.

AU - Lilly, Matthew A.

AU - Verger-Maestre, Katia

AU - Levin, Harvey S.

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AB - We evaluated the relationship of corpus callosum atrophy and/or lesions on magnetic resonance imaging (MRI) to functional hemispheric disconnection following closed head injury (CHI) in 51 pediatric patients, including mild CHI, moderate to severe CHI with extracallosal lesions, and moderate to severe CHI with callosal atrophy and/or lesions. Interhemispheric transfer of information was assessed using auditory, motor, tactile, and visual tests in patients and in 16 uninjured children. Total and regional callosal areas were measured from the midsagittal MRI slice by morphometry. The corpus callosum lesion group demonstrated a greater right ear advantage on verbal dichotic listening than all other groups. Areas of the posterior corpus callosum were negatively correlated with laterality indices of verbal dichotic listening performance and tachistoscopic identification of verbal material. The relationship of corpus callosum atrophy and/or lesions to asymmetry in dichotic listening is consistent with previous investigation of posttraumatic hemispheric disconnection effects in adults.

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Corpus callosum damage and interhemispheric transfer of information following closed head injury in children

Abstract

Keywords

ASJC Scopus subject areas

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